Insecticidal toxins from the bacterium Photorhabdus luminescens

被引：347

作者：

Bowen, D ^{[1
]}

Rocheleau, TA ^{[1
]}

Blackburn, M ^{[1
]}

Andreev, O ^{[1
]}

Golubeva, E ^{[1
]}

Bhartia, R ^{[1
]}

ffrench-Constant, RH ^{[1
]}

机构：

[1] Univ Wisconsin, Dept Entomol, Madison, WI 53706 USA

来源：

SCIENCE | 1998年 / 280卷 / 5372期

关键词：

D O I：

10.1126/science.280.5372.2129

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Transgenic plants expressing Bacillus thuringiensis (Bt) toxins are currently being deployed for insect control. In response to concerns about Bt resistance, we investigated a toxin secreted by a different bacterium Photorhabdus luminescens, which lives in the gut of entomophagous nematodes. In insects infected by the nematode, the bacteria are released into the insect hemocoel; the insect dies and the nematodes and bacteria replicate in the cadaver. The toxin consists of a series of four native complexes encoded by toxin complex loci tca, tcb, tcc, and tcd. Both tca and tcd encode complexes with high oral toxicity to Manduca sexta and therefore they represent potential alternatives to Bt for transgenic deployment.

引用

页码：2129 / 2132

页数：4

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