Olfactory nerve schwannoma: how human anatomy and electron microscopy can help to solve an intriguing scientific puzzle

被引：2

作者：

Fabbri, V. P. ^{[1
,2
]}

Papa, Valentina ^{[1
]}

Tonon, C. ^{[1
,3
]}

Agati, R. ^{[4
]}

Toni, F. ^{[4
]}

Zoli, M. ^{[1
,5
,6
]}

Mazzatenta, D. ^{[1
,5
,6
]}

Fioravanti, A. ^{[7
]}

Badaloni, F. ^{[5
]}

Cenacchi, G. ^{[1
]}

Foschini, M. P. ^{[1
,8
]}

Asioli, S. ^{[1
,6
,8
]}

机构：

[1] Univ Bologna, Dept Biomed & Neuromotor Sci, Bologna, Italy

[2] Azienda Osped Univ Modena, Dept Anat Pathol, Modena, Italy

[3] IRCCS Inst Neurol Sci Bologna, Funct & Mol Neuroimaging Unit, Bologna, Italy

[4] IRCCS Inst Neurol Sci Bologna, Programma Interaziendale Neuroradiol Con Tecn & E, Bologna, Italy

[5] IRCCS Inst Neurol Sci Bologna, Unit Neurosurg, Bologna, Italy

[6] IRCCS Inst Neurol Sci Bologna, Pituitary Unit, Bologna, Italy

[7] Cremona Hosp, Unit Neurosurg, Cremona, Italy

[8] Bellaria Hosp, Unit Pathol, Bologna, Italy

来源：

ULTRASTRUCTURAL PATHOLOGY | 2022年 / 46卷 / 05期

关键词：

Olfactory nerves; olfactory groove schwannoma; olfactory ensheathing cell tumors; nervus terminalis; electron microscopy; TUMOR;

D O I：

10.1080/01913123.2022.2101726

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

Schwannomas of the olfactory nerve are rare tumors: to the best of our knowledge, 56 cases have been previously reported. Here we describe a new patient presenting with an isolated olfactory schwannoma, highlighting the importance of multiple ancillary tests to approach the intracranial lesion of the anterior skull base, including electron microscopy. We also discuss the enigmatic origin of this entity, moving from the normal histology of the olfactory nerve compared to a peripheral nerve.

引用

页码：490 / 496

页数：7

共 16 条

[1] [Anonymous], 2021, WHO Classification of tumours, V6
[2] Schwannoma-like tumor in the anterior cranial fossa immunonegative for Leu7 but immunopositive for Schwann/2E
Bohoun, Christian Aisse
Terakawa, Yuzo
Goto, Takeo
Tanaka, Sayaka
Kuwae, Yuko
Ohsawa, Masahiko
Morisako, Hiroki
Nakajo, Kosuke
Sato, Hidetoshi
Ohata, Kenji
Yokoo, Hideaki
[J]. NEUROPATHOLOGY, 2017, 37 (03) : 265 - 271
[3] Intracranial cellular schwannomas: a clinicopathological study of 20 cases
Costa, Felipe D'Almeida
Dias, Tiago M.
Lombardo, Kara A.
Raghunathan, Aditya
Giannini, Caterina
Kenyon, Lawrence
Saad, Ali G.
Gokden, Murat
Burger, Peter C.
Montgomery, Elizabeth A.
Rodriguez, Fausto J.
[J]. HISTOPATHOLOGY, 2020, 76 (02) : 275 - 282
[4] The Puzzling Olfactory Groove Schwannoma: A Systematic Review
Figueiredo, Eberval Gadelha
Soga, Yougi
Oliveira Amorim, Robson Luis
Pereira Oliveira, Arthur Maynart
Teixeira, Manoel Jacobsen
[J]. SKULL BASE-AN INTERDISCIPLINARY APPROACH, 2011, 21 (01): : 31 - 35
[5] Helwany M., 2021, NEUROANATOMY CRANIAL
[6] JENNES L, 1987, ANN NY ACAD SCI, V519, P165
[7] JOHNSON MD, 1988, ARCH PATHOL LAB MED, V112, P155
[8] Olfactory ensheathing cell tumor with neurofibroma-like features: a case report and review of the literature
Lin, Shih-Chieh
Chen, Min-Hsiung
Lin, Chun-Fu
Ho, Donald Ming-Tak
[J]. JOURNAL OF NEURO-ONCOLOGY, 2010, 97 (01) : 117 - 122
[9] Nicolai P., 2020, ANTERIOR SKULL BASE, V84, pI, DOI [10.1159/000505414, DOI 10.1159/000505414]
[10] Solari D, 2012, TRANSL MED UNISA, V2, P36

← 1 2 →