A new N-spiro C2-symmetric chiral quaternary ammonium bromide consisting of 4,6-disubstituted biphenyl subunit as an efficient chiral phase-transfer catalyst

被引：0

作者：

Ooi, T ^{[1
]}

Kubota, Y ^{[1
]}

Maruoka, K ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Kyoto 6068502, Japan

来源：

SYNLETT | 2003年 / 12期

关键词：

chiral quaternary ammonium bromide; biphenyl subunit; glycine ester Schiff base; alkylation; alpha-amino acids;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new N-spiro chiral quaternary ammonium bromide has been designed and assembled from optically active 4,6-disubstituted biphenyl subunits. Its utility as an efficient chiral phase-transfer catalyst has been clearly demonstrated by application to the highly enantioselective alkylation of tert-butyl glycinate benzophenone Schiff base.

引用

页码：1931 / 1933

页数：3