Microdose gonadotropin-releasing hormone agonist in the absence of exogenous gonadotropins is not sufficient to induce multiple follicle development

被引：3

作者：

Chung, Karine ^{[1
]}

Fogle, Robin ^{[1
]}

Bendikson, Kristin ^{[1
]}

Christenson, Kamilee ^{[1
]}

Paulson, Richard ^{[1
]}

机构：

[1] Univ So Calif, Keck Sch Med, Div Reprod Endocrinol & Infertil, Dept Obstet & Gynecol, Los Angeles, CA 90033 USA

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 01期

关键词：

Microdose flare; controlled ovarian hyperstimulation; in vitro fertilization; GnRH agonist; poor responders; ovarian stimulation; IN-VITRO FERTILIZATION; STIMULATING-HORMONE; POOR RESPONDERS; OVULATION INDUCTION; OVARIAN-FUNCTION; FLARE; RESPONSIVENESS; PROTOCOL; INCREASE; PHASE;

D O I：

10.1016/j.fertnstert.2010.07.1081

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Because the effectiveness of the "microdose flare'' stimulation protocol often is attributed to the dramatic endogenous gonadotropin release induced by the GnRH agonist, the aim of this study was to determine whether use of microdose GnRH agonist alone could induce multiple ovarian follicle development in normal responders. Based on these data, the duration of gonadotropin rise is approximately 24 to 48 hours and is too brief to sustain continued multiple follicle growth. (Fertil Steril (R) 2011; 95:317-9. (c) 2011 by American Society for Reproductive Medicine.)

引用

页码：317 / 319

页数：3

共 18 条

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