IN VITRO ACTIVITY OF CONVENTIONAL ANTIFUNGAL AGENTS AGAINST SCEDOSPORIUM APIOSPERMUM ISOLATES RECOVERED FROM CLINICAL AND ENVIRONMENTAL SAMPLES IN NIGERIA

被引：5
|
作者：
Nweze, E. I. [1 ]
Okafor, J. I. [1 ]
机构：
[1] Univ Nigeria, Dept Microbiol, Nsukka, Nigeria
来源：
ACTA MICROBIOLOGICA ET IMMUNOLOGICA HUNGARICA | 2010年 / 57卷 / 03期
关键词：
Scedosporium apiospermum; antifungal agents; Nigeria; clinical; susceptibility testing; PSEUDALLESCHERIA-BOYDII; AMPHOTERICIN-B; VORICONAZOLE; INFECTION; PROLIFICANS; COMPLEX;
D O I：
10.1556/AMicr.57.2010.3.5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In vitro susceptibilities of Scedosporium apiospermum isolates recovered from clinical and environmental samples in Nigeria were tested against ten conventional antifungal agents, namely: amphotericin B, nystatin, flucytosine, itraconazole, posaconazole, fluconazole, voriconazole, micafungin, ketoconazole, and terbinafine using the CLSI M38-A broth dilution reference method. The isolates showed varied response/sensitivities to the antifungal agents tested. This is probably the first documented testing of Scedosporium apiospermum isolates from Africa in general and Nigeria in particular against a broad range of conventional antifungal agents.
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收藏
页码：209 / 214
页数：6
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