Gastrointestinal manifestations of systemic sclerosis: An updated review

被引:17
作者
Luquez-Mindiola, Adan [1 ]
Atuesta, Alexis Javier [2 ]
Gomez-Aldana, Andres Jose [3 ,4 ]
机构
[1] Gut Med, Dept Gastroenterol, Bogota 11711, Colombia
[2] Univ Nacl Colombia, Dept Internal Med, Bogota 11711, Colombia
[3] Santa Fe Fdn Bogota, Dept Endoscopy, Cra 7 117 15, Bogota 11711, Colombia
[4] Univ Los Andes, Fac Med, Bogota 11711, Colombia
关键词
Systemic sclerosis; Gastrointestinal; Diagnosis; Treatment; INTESTINAL BACTERIAL OVERGROWTH; GASTROESOPHAGEAL-REFLUX DISEASE; ANTRAL VASCULAR ECTASIA; EULAR SCLERODERMA TRIALS; OROFACIAL MANIFESTATIONS; FECAL INCONTINENCE; ESOPHAGEAL DISEASE; CELIAC-DISEASE; INVOLVEMENT; MANAGEMENT;
D O I
10.12998/wjcc.v9.i22.6201
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Systemic sclerosis is an autoimmune disease characterized by vascular disease, fibrosis of the skin, and internal organ dysfunction. Gastrointestinal involvement is the most frequent complication of internal organs, impacting up to 90% of patients. Gastrointestinal involvement can affect any region of the gastrointestinal tract from the mouth to the anus, with a predominance of disorders being observed at the level of the upper digestive tract. The gastrointestinal involvement primarily involves the esophagus, small bowel, and rectum. The severity of gastrointestinal involvement affects quality of life and is a marker of worse prognosis and mortality in these patients. In this review, we describe the current findings regarding gastrointestinal involvement by this entity.
引用
收藏
页码:6201 / 6217
页数:17
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