A Simple Near-Infrared Fluorescent Probe for the Detection of Peroxynitrite

被引：19

作者：

Wu, Luling ^{[1
]}

Tian, Xue ^{[1
]}

Han, Hai-Hao ^{[2
]}

Wang, Jie ^{[2
]}

Groleau, Robin R. ^{[1
]}

Tosuwan, Paramabhorn ^{[3
]}

Wannalerse, Boontana ^{[3
]}

Sedgwick, Adam C. ^{[4
]}

Bull, Steven D. ^{[1
]}

He, Xiao-Peng ^{[2
]}

James, Tony D. ^{[1
]}

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] East China Univ Sci & Technol, Key Lab Adv Mat & Joint Int Res Lab Precis Chem &, Feringa Nobel Prize Scientist Joint Res Ctr, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China

[3] Kasetsart Univ, Facultry Sci, Dept Chem, Bangkok 10900, Thailand

[4] Univ Texas Austin, Dept Chem, 105 E 24th St A5300, Autin, TX 78712 USA

来源：

CHEMISTRYOPEN | 2019年 / 8卷 / 12期

基金：

英国工程与自然科学研究理事会; 中国国家自然科学基金;

关键词：

near-infrared; fluorescence; boronate; peroxynitrite; probe; OXIDATIVE STRESS; FREE-RADICALS; IN-VIVO; SENSOR; HEALTH;

D O I：

10.1002/open.201900301

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Herein, we report the evaluation and synthesis of a reaction based fluorescent probe DCM-Bpin for the detection of peroxynitrite (ONOO-). DCM-Bpin exhibits selective fluorescence off-on response for ONOO- over other reactive oxygen species, including H2O2. Moreover, DCM-Bpin is biocompatible and has been used to visualize exogenous ONOO- in HeLa cells.

引用

收藏

页码：1407 / 1409

页数：3

相关论文

共 21 条

[1] Free radicals, oxidative stress, and antioxidants in human health and disease [J].

Aruoma, OI .

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 1998, 75 (02) :199-212

[2]

Chan J, 2012, NAT CHEM, V4, P973, DOI [10.1038/NCHEM.1500, 10.1038/nchem.1500]

[3] "Donor-Two-Acceptor" Dye Design: A Distinct Gateway to NIR Fluorescence [J].

Karton-Lifshin, Naama ;

Albertazzi, Lorenzo ;

Bendikov, Michael ;

Baran, Phil S. ;

Shabat, Doron .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (50) :20412-20420

[4] Dual excitation ratiometric fluorescent pH sensor for noninvasive bioprocess monitoring: Development and application [J].

Kermis, HR ;

Kostov, Y ;

Harms, P ;

Rao, G .

BIOTECHNOLOGY PROGRESS, 2002, 18 (05) :1047-1053

[5] Fluorescence measurements of steady state peroxynitrite production upon SIN-1 decomposition:: NADH versus dihydrodichlorofluorescein and dihydrorhodamine 123 [J].

Martin-Romero, FJ ;

Gutiérrez-Martin, Y ;

Henao, F ;

Gutiérrez-Merino, C .

JOURNAL OF FLUORESCENCE, 2004, 14 (01) :17-23

[6] Molecular Design Strategy to Construct the Near-Infrared Fluorescent Probe for Selectively Sensing Human Cytochrome P450 2J2 [J].

Ning, Jing ;

Liu, Tao ;

Dong, Peipei ;

Wang, Wei ;

Ge, Guangbo ;

Wang, Bo ;

Yu, Zhenlong ;

Shi, Lei ;

Tian, Xiangge ;

Huo, Xiaokui ;

Feng, Lei ;

Wang, Chao ;

Sun, Chengpeng ;

Cui, Jingnan ;

James, Tony D. ;

Ma, Xiaochi .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019, 141 (02) :1126-1134

[7] Tissue-Specific Near-Infrared Fluorescence Imaging [J].

Owens, Eric A. ;

Henary, Maged ;

El Fakhri, Georges ;

Choi, Hak Soo .

ACCOUNTS OF CHEMICAL RESEARCH, 2016, 49 (09) :1731-1740

[8] Nitric oxide and peroxynitrite in health and disease [J].

Pacher, Pal ;

Beckman, Joseph S. ;

Liaudet, Lucas .

PHYSIOLOGICAL REVIEWS, 2007, 87 (01) :315-424

[9] Targeting Free Radicals in Oxidative Stress-Related Human Diseases [J].

Poprac, Patrik ;

Jomova, Klaudia ;

Simunkova, Miriama ;

Kollar, Vojtech ;

Rhodes, Christopher J. ;

Valko, Marian .

TRENDS IN PHARMACOLOGICAL SCIENCES, 2017, 38 (07) :592-607

[10] Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine [J].

Radi, Rafael .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (23) :5839-5848