A long theoretical tradition has linked guilt with internalizing disorders. We find no evidence, however, that a greater personality proclivity for guilt is related to depression or eating disturbances as reported by 85 female undergraduates. Females also described guilt-producing incidents involving school versus eating and exercise. We examined reactions to the events including guilt feelings and perceived effectiveness in alleviating these feelings, intropunitive responses, action tendencies, and rationalizations. Both depression and eating disturbances were unrelated to guilt feelings over school, but were related to guilt feelings over eating and exercise. Ineffective alleviation of guilt feelings in both domains was correlated with depression and greater eating disturbances. Women who reacted to guilt-producing events with fewer intropunitive responses such as rumination and self-hatred, and by confiding in others, distancing, and rationalizing their actions through justifications and excuses were less likely to have eating disturbances.