A convenient synthetic route from isatin N-Mannich bases to nitrogen-containing derivatives of isoindigo

被引：15

作者：

Bogdanov, Andrei V. ^{[1
]}

Mironov, Vladimir F. ^{[1
]}

Musin, Lenar I. ^{[1
]}

Musin, Rashid Z. ^{[1
]}

Krivolapov, Dmitry B. ^{[1
]}

Litvinov, Igor A. ^{[1
]}

机构：

[1] Russian Acad Sci, Kazan Res Ctr, AE Arbuzov Organ & Phys Chem Inst, Kazan, Russia

来源：

MONATSHEFTE FUR CHEMIE | 2011年 / 142卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

Carbenes; Isatin; Isoindigo; Mannich bases; Phosphorus compounds; CHRONIC MYELOGENOUS LEUKEMIA; ANTIPROLIFERATIVE ACTIVITIES; ANTIBACTERIAL; MEISOINDIGO;

D O I：

10.1007/s00706-010-0416-z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of aminomethylisatins (isatin N-Mannich bases) with hexaethylphosphorous triamide leads to the formation of 1,1'-bis(dialkylaminomethyl)-3,3'-bis(indolin-3-ylidene)-2,2'-diones and 1,1'-bis(1,3-dioxo-1,3-dihydroisoindol-2-ylmethyl)-1H,1'H-[3,3']bisindolylidene-2,2'-dione.

引用

页码：81 / 85

页数：5

共 18 条

[1]

BANERJI A, 1994, INDIAN J CHEM B, V33, P532

[2] Isatin Derivatives in the Reaction with Phosphorous Hexaethyltriamide. A New Approach to the Synthesis of Isoindigo Derivatives [J].

Bogdanov, A. V. ;

Mironov, V. F. ;

Musin, L. I. ;

Buzykin, B. I. ;

Konovalov, A. I. .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2008, 78 (10) :1977-1979

[3] Deoxygenation of acenaphthenequinone with hexaethylphosphorous triamide: An efficient method of synthesis of biacenaphthylidenedione [J].

Bogdanov, AV ;

Mironov, VF ;

Buzykin, BI ;

Konovalov, AI .

RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2005, 75 (05) :825-826

[4] Synthesis and antiproliferative activities of isoindigo and azaisoindigo derivatives [J].

Bouchikhi, Fadoua ;

Anizon, Fabrice ;

Moreau, Pascale .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 43 (04) :755-762

[5] CSF ISATIN IS ELEVATED IN BULIMIA-NERVOSA [J].

BREWERTON, TD ;

ZEALBERG, JJ ;

LYDIARD, RB ;

GLOVER, V ;

SANDLER, M ;

BALLENGER, JC .

BIOLOGICAL PSYCHIATRY, 1995, 37 (07) :481-483

[6]

KORMACHEV VV, 1992, PREPARATIVE PHOSPHOR

[7] ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF ISATIN N-MANNICH BASES [J].

KUPINIC, M ;

MEDICSARIC, M ;

MOVRIN, M ;

MAYSINGER, D .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1979, 68 (04) :459-462

[8] Enterohemorrhagic Escherichia coli biofilms are inhibited by 7-hydroxyindole and stimulated by isatin [J].

Lee, Jintae ;

Bansal, Tarun ;

Jayaraman, Arul ;

Bentley, William E. ;

Wood, Thomas K. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2007, 73 (13) :4100-4109

[9]

Pandeya S. N., 2002, ARCH PHARM MED CHEM, V4, P129

[10] Antituberculous activity of norfloxacin Mannich bases with isatin derivatives [J].

Pandeya, SN ;

Sriram, D ;

Yogeeswari, P ;

Ananthan, S .

CHEMOTHERAPY, 2001, 47 (04) :266-269

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