Gastric cancer with choriocarcinoma and yolk sac tumor components: Case report

被引：17
作者：
Satake, Nobuo [1 ]
Chikakiyo, Motoya [2 ]
Yagi, Toshiyuki [2 ]
Suzuki, Yasuhiro [3 ]
Hirose, Takanori [1 ]
机构：
[1] Tokushima Prefectural Cent Hosp, Dept Diagnost Pathol, Tokushima 7708539, Japan
[2] Tokushima Prefectural Cent Hosp, Dept Surg, Tokushima 7708539, Japan
[3] Tokushima Prefectural Cent Hosp, Dept Gastroenterol, Tokushima 7708539, Japan
来源：
PATHOLOGY INTERNATIONAL | 2011年 / 61卷 / 03期
关键词：
adenocarcinoma; choriocarcinoma; germ cell tumor; stomach; yolk sac tumor; ENDODERMAL SINUS TUMOR; OF-THE-LITERATURE; HEPATOID ADENOCARCINOMA; IMMUNOHISTOCHEMICAL ANALYSIS; STOMACH; DIFFERENTIATION; CARCINOMA; FEATURES;
D O I：
10.1111/j.1440-1827.2010.02635.x
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Choriocarcinoma- and yolk sac tumor-like differentiation have rarely been reported in gastric cancers. We report a case of gastric adenocarcinoma, concurrently possessing choriocarcinoma and yolk sac tumor components, of a 74-year-old man. A hemorrhagic, 11 x 8 x 3 cm, tumor with ulceration was located in the body and pre-pylorus of the stomach. Histological examination of the resected specimens demonstrated intermingled proliferation of three different components, namely, adenocarcinoma, choriocarcinoma and yolk sac tumor, which were immunoreactive for carcinoembryonic antigen (CEA), beta-subunit of human chorionic gonadotropin (HCG) and alpha-fetoprotein (AFP), respectively. Gastric cancers with germ cell tumor components are uncommon and this is the second reported case of gastric cancer with choriocarcinoma and yolk sac tumor components.
引用
收藏
页码：156 / 160
页数：5
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