Chiral bifunctional organocatalysts in asymmetric aza-Morita-Baylis-Hillman reactions of ethyl (Arylimino)acetates with methyl vinyl ketone and ethyl vinyl ketone

被引：59
作者：
Shi, Min
Ma, Guang-Ning
Gaol, Jun
机构：
[1] Chinese Acad Sci, Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
[2] E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 25期
关键词：
D O I：
10.1021/jo701764e
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] The bifunctional chiral phosphine Lewis base (R)-2'-diphenylphosphino-[1,1'-binaphthalene]-2-ol is an effective organocatalyst in the asymmetric aza-MBH reaction of ethyl (arylimino)acetates 1 with MVK and EVK to give the corresponding adducts in moderate to good yields and good to high enantiomeric excesses under mild conditions.
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收藏
页码：9779 / 9781
页数：3
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