Well-Defined DNA Nanoparticles Templated by Self-Assembled M12L24 Molecular Spheres and Binding of Complementary Oligonucleotides

被引:56
作者
Kikuchi, Takashi
Sato, Sota
Fujita, Makoto [1 ]
机构
[1] Univ Tokyo, Dept Appl Chem, Sch Engn, Bunkyo Ku, Tokyo 1138656, Japan
关键词
COLLOIDAL NANOPARTICLES; GOLD NANOPARTICLES; AGGREGATION; PROBES;
D O I
10.1021/ja108334g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Perfectly monodisperse DNA nanoparticles were prepared via the self-assembly of 12 Pd(II) ions and 24 bidentate ligands functionalized with oligonucleotides of varying length (n = 1-3). The DNA nanoparticles formed hydrogen bonds with cDNA strands and an insoluble aggregate formed only with matching trimeric nucleotide strands (tri-A).
引用
收藏
页码:15930 / 15932
页数:3
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共 37 条
  • [1] Organization of 'nanocrystal molecules' using DNA
    Alivisatos, AP
    Johnsson, KP
    Peng, XG
    Wilson, TE
    Loweth, CJ
    Bruchez, MP
    Schultz, PG
    [J]. NATURE, 1996, 382 (6592) : 609 - 611
  • [2] Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection
    Cao, YWC
    Jin, RC
    Mirkin, CA
    [J]. SCIENCE, 2002, 297 (5586) : 1536 - 1540
  • [3] Gold Nanoparticle Self-Similar Chain Structure Organized by DNA Origami
    Ding, Baoquan
    Deng, Zhengtao
    Yan, Hao
    Cabrini, Stefano
    Zuckermann, Ronald N.
    Bokor, Jeffrey
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (10) : 3248 - +
  • [4] Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles
    Elghanian, R
    Storhoff, JJ
    Mucic, RC
    Letsinger, RL
    Mirkin, CA
    [J]. SCIENCE, 1997, 277 (5329) : 1078 - 1081
  • [5] Gene Regulation with Polyvalent siRNA-Nanoparticle Conjugates
    Giljohann, David A.
    Seferos, Dwight S.
    Prigodich, Andrew E.
    Patel, Pinal C.
    Mirkin, Chad A.
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 131 (06) : 2072 - +
  • [6] A gold nanoparticle based approach for screening triplex DNA binders
    Han, MS
    Lytton-Jean, AKR
    Mirkin, CA
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (15) : 4954 - 4955
  • [7] Nonenzymatic detection of bacterial genomic DNA using the bio bar code assay
    Hill, Haley D.
    Vega, Rafael A.
    Mirkin, Chad A.
    [J]. ANALYTICAL CHEMISTRY, 2007, 79 (23) : 9218 - 9223
  • [8] Nanoparticle-Based, Fluorous-Tag-Driven DNA Detection
    Hong, Min
    Zhou, Xin
    Lu, Zhiqiang
    Zhu, Jin
    [J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (50) : 9503 - 9506
  • [9] Peptide-coated, self-assembled M12L24 coordination spheres and their immobilization onto an inorganic surface
    Ikemi, Masatoshi
    Kikuchi, Takashi
    Matsumura, Sachiko
    Shiba, Kiyotaka
    Sato, Sota
    Fujita, Makoto
    [J]. CHEMICAL SCIENCE, 2010, 1 (01) : 68 - 71
  • [10] DNA-controlled assembly of soft nanoparticles
    Jakobsen, Ulla
    Simonsen, Adam C.
    Vogel, Stefan
    [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (32) : 10462 - +