Recurrent respiratory papillomatosis: current and future perspectives

被引:106
作者
Carifi, Marco [1 ]
Napolitano, Domenico [1 ]
Morandi, Morando [1 ]
Dall'Olio, Danilo [2 ]
机构
[1] Azienda Osped Rilievo Nazl A Cardarelli, Dept Otolaryngol, I-80131 Naples, Italy
[2] Osped Maggiore CA Pizzardi, Dept Otolaryngol, Bologna, Italy
关键词
recurrent respiratory papillomatosis; laryngeal papillomatosis; adjuvant; cidofovir; bevacizumab; photodynamic therapy; microdebrider; angiolytic laser; celecoxib; HspE7; JUVENILE LARYNGEAL PAPILLOMATOSIS; HUMAN-PAPILLOMAVIRUS INFECTION; OF-THE-LITERATURE; INTRALESIONAL CIDOFOVIR; PHOTODYNAMIC THERAPY; RISK-FACTORS; BEVACIZUMAB AVASTIN; LASER TREATMENT; BIPHASIC VESICLES; NATIONAL REGISTRY;
D O I
10.2147/TCRM.S81825
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Although recurrent respiratory papillomatosis is a benign disease of the upper aerodigestive tract caused by infection with human papillomavirus, the disease process is unpredictable, ranging from mild disease and spontaneous remission to an aggressive disease with pulmonary spread and requirement for frequent surgical debulking procedures. It can present a protracted clinical course and cause potentially life-threatening compromise of the airways. Over recent decades, a number of alternative medical therapies to standard surgical treatment have been investigated, with modest outcomes overall. Currently, some additional therapies are being explored, together with novel surgical instrumentation that can help to avoid inevitable long-term stenotic complications, ultimately affecting quality of life. Hopefully, clinicians might soon be able to significantly improve the quality of treatment and outcomes for patients affected with recurrent respiratory papillomatosis, with human papillomavirus vaccination having a potentially important role.
引用
收藏
页码:731 / 738
页数:8
相关论文
共 104 条
[1]   Human papillomavirus in larynx [J].
Aaltonen, LM ;
Rihkanen, H ;
Vaheri, A .
LARYNGOSCOPE, 2002, 112 (04) :700-707
[2]  
ABRAMSON AL, 1994, ARCH OTOLARYNGOL, V120, P852
[3]  
ABRAMSON AL, 1992, ARCH OTOLARYNGOL, V118, P25
[4]   Stepped-dose protocol of cidofovir therapy in recurrent respiratory papillomatosis in children [J].
Akst, LM ;
Lee, W ;
Discolo, C ;
Knott, D ;
Younes, A ;
Koltai, PJ .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2003, 129 (08) :841-846
[5]   Initial results from the national registry for juvenile-onset recurrent respiratory papillomatosis [J].
Armstrong, LR ;
Derkay, CS ;
Reeves, WC .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 1999, 125 (07) :743-748
[6]   THE USE OF CIS-RETINOIC ACID IN RECURRENT RESPIRATORY PAPILLOMATOSIS OF THE LARYNX - A RANDOMIZED PILOT-STUDY [J].
BELL, R ;
WAUN, KH ;
ITRI, LM ;
MCDONALD, G ;
STRONG, MS .
AMERICAN JOURNAL OF OTOLARYNGOLOGY, 1988, 9 (04) :161-164
[7]   HUMAN PAPILLOMAVIRUSES - ASSOCIATIONS BETWEEN LARYNGEAL PAPILLOMAS AND GENITAL WARTS [J].
BENNETT, RS ;
POWELL, KR .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1987, 6 (03) :229-232
[8]   Safety and Dosing of Bevacizumab (Avastin) for the Treatment of Recurrent Respiratory Papillomatosis [J].
Best, Simon R. ;
Friedman, Aaron D. ;
Landau-Zemer, Tali ;
Barbu, Anca M. ;
Burns, James A. ;
Freeman, Mason W. ;
Halvorsen, Yuan-Di ;
Hillman, Robert E. ;
Zeitels, Steven M. .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 2012, 121 (09) :587-593
[9]   Recurrent respiratory papillomatosis: a complex defect in immune responsiveness to human papillomavirus-6 and-11 [J].
Bonagura, Vincent R. ;
Hatam, Lynda J. ;
Rosenthal, David W. ;
De Voti, James A. ;
Lam, Fung ;
Steinberg, Bettie M. ;
Abramson, Allan L. .
APMIS, 2010, 118 (6-7) :455-470
[10]   ENRICHED HLA-DQ3 PHENOTYPE AND DECREASED CLASS-I MAJOR HISTOCOMPATIBILITY COMPLEX ANTIGEN EXPRESSION IN RECURRENT RESPIRATORY PAPILLOMATOSIS [J].
BONAGURA, VR ;
SIEGAL, FP ;
ABRAMSON, AL ;
SANTIAGOSCHWARZ, F ;
OREILLY, ME ;
SHAH, K ;
DRAKE, D ;
STEINBERG, BM .
CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 1994, 1 (03) :357-360