Retrieval of 3D information in X-ray dark-field imaging with a large field of view

被引:2
作者
Andrejewski, Jana [1 ,2 ]
De Marco, Fabio [1 ,2 ]
Willer, Konstantin [1 ,2 ,5 ,6 ]
Noichl, Wolfgang [1 ,2 ]
Urban, Theresa [1 ,2 ,5 ,6 ]
Frank, Manuela [1 ,2 ,5 ,6 ]
Gustschin, Alex [1 ,2 ]
Meyer, Pascal [3 ]
Koehler, Thomas [4 ]
Pfeiffer, Franz [1 ,2 ,5 ,6 ,7 ]
Herzen, Julia [1 ,2 ]
机构
[1] Tech Univ Munich, Sch Nat Sci, Dept Phys, Chair Biomed Phys, D-85748 Garching, Germany
[2] Tech Univ Munich, Munich Inst Biomed Engn, D-85748 Garching, Germany
[3] Karlsruhe Inst Technol, Inst Microstruct Technol, D-76344 Eggenstein Leopoldshafen, Germany
[4] Philips GmbH Innovat Technol, Res Labs, D-22335 Hamburg, Germany
[5] Tech Univ Munich, Sch Med, Dept Diagnost & Intervent Radiol, D-81675 Munich, Germany
[6] Tech Univ Munich, Klinikum Rechts Isar, D-81675 Munich, Germany
[7] Tech Univ Munich, Inst Adv Study, D-85748 Garching, Germany
基金
欧洲研究理事会;
关键词
PHASE-CONTRAST; TOMOSYNTHESIS; TOMOGRAPHY;
D O I
10.1038/s41598-021-02960-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
X-ray dark-field imaging is a widely researched imaging technique, with many studies on samples of very different dimensions and at very different resolutions. However, retrieval of three-dimensional (3D) information for human thorax sized objects has not yet been demonstrated. We present a method, similar to classic tomography and tomosynthesis, to obtain 3D information in X-ray -imaging. Here, the sample is moved through the divergent beam of a Talbot-Lau interferometer. Projections of features at different distances from the source seemingly move with different velocities over the detector, due to the cone beam geometry. The reconstruction of different focal planes exploits this effect. We imaged a chest phantom and were able to locate different features in the sample (e.g. the ribs, and two sample vials filled with water and air and placed in the phantom) to corresponding focal planes. Furthermore, we found that image quality and detectability of features is sufficient for image reconstruction with a dose of 68 mu Sv at an effective pixel size of 0.357 x 0.357 mm(2). Therefore, we successfully demonstrated that the presented method is able to retrieve 3D information in X-ray dark-field imaging.
引用
收藏
页数:8
相关论文
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