NMR methods for studying quadruplex nucleic acids

被引：106
作者：
da Silva, Mateus Webba [1 ]
机构：
[1] Univ Ulster, Sch Biomed Sci, Coleraine BT52 1SA, Londonderry, North Ireland
来源：
METHODS | 2007年 / 43卷 / 04期
关键词：
NMR; quadruplexes; trans-hydrogen bonds; residual dipolar couplings; dynamics; structure calculation;
D O I：
10.1016/j.ymeth.2007.05.007
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Solution NMR spectroscopy has traditionally played a central role in examining quadruplex structure, dynamics, and interactions. Here, an overview is given of the methods currently applied to structural, dynamics, thermodynamics, and kinetics studies of nucleic acid quadruplexes and associated cations. (c) 2007 Elsevier Inc. All rights reserved.
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页码：264 / 277
页数：14
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