Antibody-targeted nanoparticles for cancer treatment

被引：54
作者：
Carter, Thomas [1 ]
Mulholland, Paul [1 ,2 ]
Chester, Kerry [1 ]
机构：
[1] UCL, UCL Canc Inst, London, England
[2] Univ Coll London Hosp NHS Fdn Trust, London, England
来源：
IMMUNOTHERAPY | 2016年 / 8卷 / 08期
关键词：
antibodies; cancer treatment; clinical translation; hyperthermia; nanoparticles; targeting; theranostics; WALLED CARBON NANOTUBES; DRUG-DELIVERY SYSTEMS; STEM-LIKE CELLS; GOLD NANOPARTICLES; MAGNETIC NANOPARTICLES; MONOCLONAL-ANTIBODY; PLGA NANOPARTICLES; PHOTOTHERMAL THERAPY; PANCREATIC-CANCER; MEMBRANE ANTIGEN;
D O I：
10.2217/imt.16.11
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Nanoparticles (NPs) are diverse and versatile with physical properties that can be employed for use in cancer medicine. Targeting NPs using antibodies and antibody fragments could overcome some of the limitations seen with current targeted therapies. This review will discuss the role of antibody-targeted NPs in the treatment of cancer: as delivery vehicles, targeted theranostic agents and in the evolving field of cancer hyperthermia.
引用
收藏
页码：941 / 958
页数：18
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