Synthesis of CD-ring modified 1 alpha,25-dihydroxy vitamin D analogues: E-ring analogues

被引:28
|
作者
Sabbe, K
DHallewyn, C
DeClercq, P
Vandewalle, M
机构
[1] STATE UNIV GHENT,DEPT ORGAN CHEM,ORGAN SYNTH LAB,B-9000 GHENT,BELGIUM
[2] KATHOLIEKE UNIV LEUVEN,LAB EXPTL GENEESKUNDE ENDOCRINOL,B-3030 LOUVAIN,BELGIUM
关键词
D O I
10.1016/0960-894X(96)00300-9
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Vitamin D analogues, characterized by the absence of both C- and D-rings and by the presence of a five-membered ring formed by connecting C-12 and C-21 (E-ring analogues) are described. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码:1697 / 1702
页数:6
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