Primary Central Nervous System Vasculitis With Optic Nerve Involvement

被引:9
作者
Benson, Christy E. [1 ]
Knezevic, Alexander [1 ]
Lynch, Shannon C. [1 ]
机构
[1] Univ Nebraska Med Ctr, Coll Med, Dept Ophthalmol, Omaha, NE USA
关键词
GRANULOMATOUS-ANGIITIS; ENHANCEMENT;
D O I
10.1097/WNO.0000000000000328
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
A 20-year-old woman presented with headache, decreased vision, eye pain, and urinary retention. During her clinical course, visual acuity declined to 20/800, right eye, and 20/50, left eye, associated with bilateral optic disc edema. Brain magnetic resonance imaging revealed enhancement of the leptomeninges, right optic nerve, and right side of the optic chiasm. Extensive evaluation of the central nervous system (CNS) for an infectious cause was negative. Brain biopsy showed a pattern consistent with vasculitis. The patient was treated with prednisone and cyclophosphamide, resulting in improvement of her vision and systemic symptoms. Primary CNS vasculitis is a rare condition that may affect the anterior visual pathways. (C) 2015 by North American Neuro- Ophthalmology Society
引用
收藏
页码:174 / 177
页数:4
相关论文
共 18 条
[1]   GRANULOMATOUS ANGIITIS - UNUSUAL ETIOLOGY OF STROKE [J].
BURGER, PC ;
BURCH, JG ;
VOGEL, FS .
STROKE, 1977, 8 (01) :29-35
[2]  
Calabrese LH, 1997, ARTHRITIS RHEUM, V40, P1189, DOI 10.1002/art.2
[3]   PRIMARY ANGIITIS OF THE CENTRAL NERVOUS-SYSTEM - REPORT OF 8 NEW CASES, REVIEW OF THE LITERATURE, AND PROPOSAL FOR DIAGNOSTIC-CRITERIA [J].
CALABRESE, LH ;
MALLEK, JA .
MEDICINE, 1988, 67 (01) :20-39
[4]   NONINFECTIOUS GRANULOMATOUS ANGIITIS WITH A PREDILECTION FOR THE NERVOUS SYSTEM [J].
CRAVIOTO, H ;
FEIGIN, I .
NEUROLOGY, 1959, 9 (09) :599-609
[5]   Primary central nervous system vasculitis: pathology and mechanisms [J].
Giannini, Caterina ;
Salvarani, Carlo ;
Hunder, Gene ;
Brown, Robert D. .
ACTA NEUROPATHOLOGICA, 2012, 123 (06) :759-772
[6]   Primary angiitis of the central nervous system [J].
Hajj-Ali, Rula A. ;
Calabrese, Leonard H. .
AUTOIMMUNITY REVIEWS, 2013, 12 (04) :463-466
[7]   Linear magnetic resonance enhancement and optic neuropathy in primary angiitis of the central nervous system [J].
Hassan, AS ;
Trobe, JD ;
McKeever, PE ;
Gebarski, SS .
JOURNAL OF NEURO-OPHTHALMOLOGY, 2003, 23 (02) :127-131
[8]  
Hughes JT, 1996, NEUROLOGY, V16, P293
[9]   GIANT-CELL GRANULOMATOUS ANGIITIS OF CENTRAL NERVOUS-SYSTEM [J].
JELLINGER, K .
JOURNAL OF NEUROLOGY, 1977, 215 (03) :175-190
[10]   GRANULOMATOUS ANGIITIS OF CENTRAL NERVOUS SYSTEM [J].
KOLODNY, EH ;
REBEIZ, JJ ;
CAVINESS, VS ;
RICHARDSON, EP .
ARCHIVES OF NEUROLOGY, 1968, 19 (05) :510-+