Mirror neuron system: Basic findings and clinical applications

被引:180
作者
Iacoboni, Marco
Mazziotta, John C.
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human Behav,Ahmanson Lovela, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human Behav,Dept Psychiat, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human BehaDept Biobehav Sci, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human Behav,Dept Neurol, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human Behav,Dept Pharmacol, Los Angeles, CA 90095 USA
[6] Univ Calif Los Angeles, David Geffen Sch Med, Brain Res Inst, Semel Inst Neurosci & Human Behav,Dept Radiol Sci, Los Angeles, CA 90095 USA
关键词
D O I
10.1002/ana.21198
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
In primates, ventral premotor and rostral inferior parietal neurons fire during the execution of hand and mouth actions. Some cells (called mirror neurons) also fire when hand and mouth actions are just observed. Mirror neurons provide a simple neural mechanism for understanding the actions of others. In humans, posterior inferior frontal and rostral inferior parietal areas have mirror properties. These human areas are relevant to imitative learning and social behavior. indeed, the socially isolating condition of autism is associated with a deficit in mirror neuron areas. Strategies inspired by mirror neuron research recently have been used in the treatment of autism and in motor rehabilitation after stroke.
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页码:213 / 218
页数:6
相关论文
共 66 条
[1]  
ALTSCHULER EL, 2000, ABSTR SOC NEUROSCI, V68, P1
[2]   Transcranial magnetic stimulation highlights the sensorimotor side of empathy for pain [J].
Avenanti, A ;
Bueti, D ;
Galati, G ;
Aglioti, SM .
NATURE NEUROSCIENCE, 2005, 8 (07) :955-960
[3]   Congruent embodied representations for visually presented actions and linguistic phrases describing actions [J].
Aziz-Zadeh, Lisa ;
Wilson, Stephen M. ;
Rizzolatti, Giacomo ;
Iacoboni, Marco .
CURRENT BIOLOGY, 2006, 16 (18) :1818-1823
[4]   SACCADE-RELATED ACTIVITY IN THE LATERAL INTRAPARIETAL AREA .2. SPATIAL PROPERTIES [J].
BARASH, S ;
BRACEWELL, RM ;
FOGASSI, L ;
GNADT, JW ;
ANDERSEN, RA .
JOURNAL OF NEUROPHYSIOLOGY, 1991, 66 (03) :1109-1124
[5]   SACCADE-RELATED ACTIVITY IN THE LATERAL INTRAPARIETAL AREA .1. TEMPORAL PROPERTIES - COMPARISON WITH AREA 7A [J].
BARASH, S ;
BRACEWELL, RM ;
FOGASSI, L ;
GNADT, JW ;
ANDERSEN, RA .
JOURNAL OF NEUROPHYSIOLOGY, 1991, 66 (03) :1095-1108
[6]   UNILATERAL NEGLECT - PERSONAL AND EXTRA-PERSONAL [J].
BISIACH, E ;
PERANI, D ;
VALLAR, G ;
BERTI, A .
NEUROPSYCHOLOGIA, 1986, 24 (06) :759-767
[7]   PRIMATE FRONTAL EYE FIELDS .1. SINGLE NEURONS DISCHARGING BEFORE SACCADES [J].
BRUCE, CJ ;
GOLDBERG, ME .
JOURNAL OF NEUROPHYSIOLOGY, 1985, 53 (03) :603-635
[8]   Neural circuits underlying imitation learning of hand actions: An event-related fMRI study [J].
Buccino, G ;
Vogt, S ;
Ritzl, A ;
Fink, GR ;
Zilles, K ;
Freund, HJ ;
Rizzolatti, G .
NEURON, 2004, 42 (02) :323-334
[9]   Functions of the mirror neuron system: Implications for neurorehabilitation [J].
Buccino, Giovanni ;
Solodkin, Ana ;
Small, Steven L. .
COGNITIVE AND BEHAVIORAL NEUROLOGY, 2006, 19 (01) :55-63
[10]   Action observation and acquired motor skills:: An fMRI study with expert dancers [J].
Calvo-Merino, B ;
Glaser, DE ;
Grèzes, J ;
Passingham, RE ;
Haggard, P .
CEREBRAL CORTEX, 2005, 15 (08) :1243-1249