Hypothalamic-related neural mechanism in lifelong premature ejaculation and trends following selective serotonin reuptake inhibitor administration

被引：1

作者：

Geng, Bowen ^{[1
,2
]}

Gao, Ming ^{[3
]}

Xu, Ke ^{[1
,2
]}

Zhang, Shuming ^{[1
,2
]}

Liu, Peng ^{[1
,2
]}

机构：

[1] Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China

[2] Xidian Univ, Minist Educ, Sch Life Sci & Technol, Engn Res Ctr Mol & Neuro Imaging, Xian, Shaanxi, Peoples R China

[3] Yanan Univ, Dept Urol, XiAn Daxing Hosp, Yanan, Peoples R China

来源：

CNS NEUROSCIENCE & THERAPEUTICS | 2022年 / 28卷 / 09期

基金：

中国国家自然科学基金;

关键词：

DAPOXETINE;

D O I：

10.1111/cns.13882

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Lifelong premature ejaculation patients had altered structural and functional parameters of the hypothalamus compared with healthy controls. The patients showed increased hypothalamus-related functional connectivity in several regions one hour after dapoxetine administration. The changing trends of the brain functional connectivity after dapoxetine administration possibly provided important information about the selective serotonin reuptake inhibitor effects on the functional neural system.

引用

页码：1461 / 1463

页数：3

共 25 条

[1] Deleterious effects of selective serotonin reuptake inhibitor treatment on semen parameters in patients with lifelong premature ejaculation
H Koyuncu
E C Serefoglu
A T Ozdemir
W J Hellstrom
International Journal of Impotence Research, 2012, 24 : 171 - 173
[2] Deleterious effects of selective serotonin reuptake inhibitor treatment on semen parameters in patients with lifelong premature ejaculation
Koyuncu, H.
Serefoglu, E. C.
Ozdemir, A. T.
Hellstrom, W. J.
INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH, 2012, 24 (05) : 171 - 173
[3] Efficacy of selective serotonin reuptake inhibitor (SSRI) in patient with premature ejaculation
Rezakhaniha, Bijan
Sirosbakht, Soheila
IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE, 2010, 8 (02) : 55 - 59
[4] Duloxetine, dual serotonin and norepinephrine reuptake inhibitor, versus paroxetine, selective serotonin reuptake inhibitor, in the treatment for premature ejaculation
Levent Ozcan
Emre Can Polat
Alper Otunctemur
Emin Ozbek
International Urology and Nephrology, 2015, 47 : 283 - 287
[5] Duloxetine, dual serotonin and norepinephrine reuptake inhibitor, versus paroxetine, selective serotonin reuptake inhibitor, in the treatment for premature ejaculation
Ozcan, Levent
Polat, Emre Can
Otunctemur, Alper
Ozbek, Emin
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2015, 47 (02) : 283 - 287
[6] The effect of plasma melatonin levels in the treatment of lifelong premature ejaculation with selective serotonin reuptake inhibitors
Kalkanli, Arif
Gezmis, Cem Tugrul
Fikri, Onur
Cilesiz, Nusret Can
Ozkan, Arif
Eroglu, Ali
Aydin, Memduh
ANDROLOGIA, 2020, 52 (11)
[7] Efficacy of sildenafil as adjuvant therapy to selective serotonin reuptake inhibitor in alleviating premature ejaculation
Chen, JZ
Mabjeesh, NJ
Matzkin, H
Greenstein, A
UROLOGY, 2003, 61 (01) : 197 - 200
[8] Comparison of paroxetine and dapoxetine, a novel selective serotonin reuptake inhibitor in the treatment of premature ejaculation
Simsek, Abdulmuttalip
Kirecci, Sinan Levent
Kucuktopcu, Onur
Ozgor, Faruk
Akbulut, Mehmet Fatih
Sarilar, Omer
Ozkuvanci, Unsal
Gurbuz, Zafer Gokhan
ASIAN JOURNAL OF ANDROLOGY, 2014, 16 (05) : 725 - 727
[9] COMPARISON OF PAROXETINE AND DAPOXETINE, A NOVEL SELECTIVE SEROTONIN REUPTAKE INHIBITOR, IN THE TREATMENT OF PREMATURE EJACULATION
Simsek, Abdulmuttalip
Sarilar, Omer
Kirecci, Sinan
Kucuktopcu, Onur
Ozgor, Faruk
Akbulut, Fatih
Sonmezay, Erkan
Berberoglu, Yalcyn
Gurbuz, Gokhan
JOURNAL OF UROLOGY, 2014, 191 (04): : E534 - E534
[10] The upregulation of tryptophan hydroxylase-2 expression is important for premature ejaculation treatment with the selective serotonin reuptake inhibitor
Zhu, Tianle
Gao, Pan
Gao, Jingjing
Liu, Xi
Jiang, Hui
Zhang, Xiansheng
ANDROLOGY, 2022, 10 (03) : 595 - 603

← 1 2 3 →