Synthesis and study of amino acid based phosphinite ligands

被引：32

作者：

Galka, PW ^{[1
]}

Kraatz, HB ^{[1
]}

机构：

[1] Univ Saskatchewan, Dept Chem, Saskatoon, SK S7N 5C9, Canada

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2003年 / 674卷 / 1-2期

基金：

加拿大自然科学与工程研究理事会;

关键词：

phosphinite; amino acid; peptide; platinum; palladium; X-ray; P-31-NMR;

D O I：

10.1016/S0022-328X(03)00181-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The preparation of the five new amino acid derived phosphinites Boc-Ser(OPPh2)-OMe (5), Boc-Thr(OPPh2)-OMe (6), Boc-Tyr(OPPh2)-OMe (7), Z-Ser(OPPh2)-OMe (8), and Z-beta-Ala-Tyr(OPPh2)-OMe (9) is reported together with their full spectroscopic characterization. These ligands readily complex to Pd(II) and Pt(II) giving the corresponding complexes [Boc-Ser(OPPh2)OMe](2)PtCl2 (10), [Boc-Tyr(OPPh2)-OMe](2)PtCl2 (11), [Boc-Thr(OPPh2)-OMe](2)PtCl2 (12), [Z-P-Ala-Tyr(OPPh2)-OMe](2)PtCl2 (13), [Boc-Ser(OPPh2)-OMe](2)PdCl2 (14), [Boc-Tyr(OPPh2)-OMe](2)PdCl2 (15), [Boc-Thr(OPPh2)-OMe](2)PdCl2 (16), [Z-beta-Ala-Tyr(OPPh2)OMe](2)-PdCl2-(17). The X-ray structure of 10 was determined and shows the ligands being cis coordinated around the Pt(II) center with Pt-P distances of 2.2278(13) Angstrom for Pt-P(1) and 2.2235(12) Angstrom for Pt-P(2). (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：24 / 31

页数：8

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