P38 MAPK Inhibition Protects against FFA-Induced Insulin Resistance and Hepatic Fat Accumulation

被引:1
|
作者
Joseph, Deborah Y.
Rivers, Sydney L.
Giacca, Adria
机构
基金
加拿大健康研究院;
关键词
D O I
10.2337/db20-1858-P
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1858-P
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Inhibition of NOD1 signalling protects against saturated-fat induced insulin resistance
    Shoaib, F.
    Tan, Y.
    Giacca, A.
    DIABETOLOGIA, 2020, 63 (SUPPL 1) : S219 - S219
  • [22] Myocardial Activation of p38 alpha MAPK Results in Cardiac Insulin Resistance by Chronic Insulin Signaling
    Qi, Yajuan
    Dostal, Davide
    Guo, Shaodong
    FASEB JOURNAL, 2013, 27
  • [23] Carboxymethylated chitosan protects rat chondrocytes from NO-induced apoptosis via inhibition of the p38/MAPK signaling pathway
    He, Bin
    Tao, Haiying
    Liu, Shiqing
    Wei, Ailin
    Pan, Feng
    Chen, Ren
    Li, Xiaohai
    MOLECULAR MEDICINE REPORTS, 2016, 13 (03) : 2151 - 2158
  • [24] DHEA treatment reduces fat accumulation and protects against insulin resistance in male rats
    Han, DH
    Hansen, PA
    Chen, MM
    Holloszy, JO
    JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 1998, 53 (01): : B19 - B24
  • [25] Antisense Oligonucleotide Knockdown of PEPCK Protects Against Fat Induced Obesity but Results in Hepatic Steatosis and Insulin Resistance
    Beddow, Sara A.
    Majumdar, Sachin
    Topchyan, Katarina
    Cline, Gary W.
    Manchem, Prasad
    Monia, Brett P.
    Bhanot, Sanjay
    Shulman, Gerald I.
    Samuel, Varman T.
    DIABETES, 2011, 60 : A434 - A434
  • [26] Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance
    Cheng, Pei-Wen
    Lin, Yu-Te
    Ho, Wen-Yu
    Lu, Pei-Jung
    Chen, Hsin-Hung
    Lai, Chi-Cheng
    Sun, Gwo-Ching
    Yeh, Tung-Chen
    Hsiao, Michael
    Tseng, Ching-Jiunn
    Liu, Chun-Peng
    FREE RADICAL BIOLOGY AND MEDICINE, 2017, 112 : 298 - 307
  • [27] Lipoxin A4-Mediated p38 MAPK Signaling Pathway Protects Mice Against Collagen-Induced Arthritis
    Li, Jinyu
    Sun, Qi
    Zheng, Chenying
    Bai, Chunxiao
    Liu, Chuyin
    Zhao, Xueqian
    Deng, Peiying
    Chai, Limin
    Jia, Yusong
    BIOCHEMICAL GENETICS, 2021, 59 (01) : 346 - 365
  • [28] Lipoxin A4-Mediated p38 MAPK Signaling Pathway Protects Mice Against Collagen-Induced Arthritis
    Jinyu Li
    Qi Sun
    Chenying Zheng
    Chunxiao Bai
    Chuyin Liu
    Xueqian Zhao
    Peiying Deng
    Limin Chai
    Yusong Jia
    Biochemical Genetics, 2021, 59 : 346 - 365
  • [29] p38 MAPK inhibition reduces diabetes-induced impairment of wound healing
    Medicherla, Satyanarayana
    Wadsworth, Scott
    Cullen, Breda
    Silcock, Derek
    Ma, Jing Y.
    Mangadu, Ruban
    Kerr, Irene
    Chakravarty, Sarvajit
    Luedtke, Gregory L.
    Dugar, Sundeep
    Protter, Andrew A.
    Higgins, Linda S.
    DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2009, 2 : 91 - 100
  • [30] Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine
    Chen, Jiann-Hwa
    Kuo, Hsing-Chun
    Lee, Kam-Fai
    Tsai, Tung-Hu
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 279 (03) : 294 - 302