Nanoparticles for immune system targeting

被引：43
作者：
Du, Juan [1 ]
Zhang, Yu Shrike [2 ]
Hobson, Divia [3 ]
Hydbring, Per [4 ]
机构：
[1] Karolinska Inst, Dept Microbiol Tumor & Cell Biol, CTMR, S-17177 Stockholm, Sweden
[2] Harvard Med Sch, Brigham & Womens Hosp, Div Engn Med, Dept Med, Cambridge, MA 02139 USA
[3] Xi An Jiao Tong Univ, Sch Life Sci & Technol, Xian 710049, Shaanxi, Peoples R China
[4] Karolinska Inst, Dept Oncol Pathol, S-17176 Stockholm, Sweden
来源：
DRUG DISCOVERY TODAY | 2017年 / 22卷 / 09期
关键词：
MESOPOROUS SILICA NANOPARTICLES; LYMPH-NODE MICROENVIRONMENT; VACCINE DELIVERY; DRUG-DELIVERY; ENHANCED ANTITUMOR; ADAPTIVE IMMUNITY; DENDRITIC CELLS; T-LYMPHOCYTES; ANTIGEN; INNATE;
D O I：
10.1016/j.drudis.2017.03.013
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Nanoparticles (NPs) are found in numerous applications used to modulate the immune system. They serve as drug delivery carriers or vaccine adjuvants and are utilized as therapeutics against a variety of diseases. NPs can be engineered to target distinct cellular components representing multiple pathways of immunity. The combination of NPs with immune system targeting moieties has paved the way for improved targeted immune therapies. Here we provide an update of recent progress in this field.
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收藏
页码：1295 / 1301
页数：7
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