A Conserved Archaeal Pathway for Tail-Anchored Membrane Protein Insertion

被引：12

作者：

Sherrill, John ^{[1
]}

Mariappan, Malaiyalam ^{[2
]}

Dominik, Pawel ^{[1
]}

Hegde, Ramanujan S. ^{[2
]}

Keenan, Robert J. ^{[1
]}

机构：

[1] Univ Chicago, Dept Biochem & Mol Biol, Gordon Ctr Integrat Sci, Chicago, IL 60637 USA

[2] NICHHD, Cell Biol & Metab Program, NIH, Bethesda, MD 20892 USA

来源：

TRAFFIC | 2011年 / 12卷 / 09期

关键词：

archaea; ArsA; Get3; insertion; posttranslational; targeting; tail-anchored membrane proteins; TRC40; BINDING; COMPLEX; GET3;

D O I：

10.1111/j.1600-0854.2011.01229.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Eukaryotic tail-anchored ( TA) membrane proteins are inserted into the endoplasmic reticulum by a posttranslational TRC40 pathway, but no comparable pathway is known in other domains of life. The crystal structure of an archaebacterial TRC40 sequence homolog bound to ADP.AlF4- reveals characteristic features of eukaryotic TRC40, including a zinc-mediated dimer and a large hydrophobic groove. Moreover, archaeal TRC40 interacts with the transmembrane domain of TA substrates and directs their membrane insertion. Thus, the TRC40 pathway is more broadly conserved than previously recognized.

引用

页码：1119 / 1123

页数：5

共 50 条

[41] Tail-anchored Protein Insertion in Mammals FUNCTION AND RECIPROCAL INTERACTIONS OF THE TWO SUBUNITS OF THE TRC40 RECEPTOR
Colombo, Sara Francesca
Cardani, Silvia
Maroli, Annalisa
Vitiello, Adriana
Soffientini, Paolo
Crespi, Arianna
Bram, Richard F.
Benfante, Roberta
Borgese, Nica
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016, 291 (29) : 15292 - 15306
[42] Capture and delivery of tail-anchored proteins to the endoplasmic reticulum
Farkas, Akos
Bohnsack, Katherine E.
JOURNAL OF CELL BIOLOGY, 2021, 220 (08):
[43] The emerging role of calcium-modulating cyclophilin ligand in posttranslational insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Yamamoto, Yasunori
Sakisaka, Toshiaki
JOURNAL OF BIOCHEMISTRY, 2015, 157 (06): : 419 - 429
[44] Targeting of tail-anchored proteins to Trichomonas vaginalis hydrogenosomes
Rada, Petr
Makki, Abhijith
Zarsky, Vojtech
Tachezy, Jan
MOLECULAR MICROBIOLOGY, 2019, 111 (03) : 588 - 603
[45] mRNA encoding Sec61β, a tail-anchored protein, is localized on the endoplasmic reticulum
Cui, Xianying A.
Zhang, Hui
Ilan, Lena
Liu, Ai Xin
Kharchuk, Iryna
Palazzo, Alexander F.
JOURNAL OF CELL SCIENCE, 2015, 128 (18) : 3398 - 3410
[46] Model for eukaryotic tail-anchored protein binding based on the structure of Get3
Suloway, Christian J. M.
Chartron, Justin W.
Zaslaver, Ma'ayan
Clemons, William M., Jr.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (35) : 14849 - 14854
[47] New insights into the targeting of a subset of tail-anchored proteins to the outer mitochondrial membrane
Marty, Naomi J.
Teresinski, Howard J.
Hwang, Yeen Ting
Clendening, Eric A.
Gidda, Satinder K.
Sliwinska, Elwira
Zhang, Daiyuan
Miernyk, Jan A.
Brito, Glauber C.
Andrews, David W.
Dyer, John M.
Mullen, Robert T.
FRONTIERS IN PLANT SCIENCE, 2014, 5
[48] Mutation of wrb, a Component of the Guided Entry of Tail-Anchored Protein Pathway, Disrupts Photoreceptor Synapse Structure and Function
Daniele, Lauren L.
Emran, Farida
Lobo, Glenn P.
Gaivin, Robert J.
Perkins, Brian D.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (07) : 2942 - 2954
[49] Role of Hsp70 in Post-Translational Protein Targeting: Tail-Anchored Membrane Proteins and Beyond
Shan, Shu-ou
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (02)
[50] Development of a prediction system for tail-anchored proteins
Shigemitsu, Shunsuke
Cao, Wei
Terada, Tohru
Shimizu, Kentaro
BMC BIOINFORMATICS, 2016, 17

← 1 2 3 4 5 →