Managing a Case of Extensively Drug-Resistant (XDR) Pulmonary Tuberculosis in Singapore

被引:0
作者
Phua, Chee Kiang [1 ]
Chee, Cynthia B. E. [1 ]
Chua, Angeline P. G. [1 ]
Gan, Suay Hong [1 ]
Ahmed, Aneez D. B. [2 ]
Wang, Yee Tang [1 ]
机构
[1] Tan Tock Seng Hosp, TB Control Unit, Singapore 308087, Singapore
[2] Tan Tock Seng Hosp, Dept Gen Surg Thorac, Singapore 308087, Singapore
关键词
Directly observed therapy; Multidrug-resistant; Mycobacteria; MULTIDRUG-RESISTANT; SURGERY;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: Extensively drug-resistant tuberculosis (XDR-TB) is an emerging global health risk. We present the first case report of XDR-TB in Singapore. Clinical Picture: A 41-year-old Indonesian lady with previously treated pulmonary tuberculosis presented with chronic cough. Her sputum was strongly acid-fast bacilli positive and grew Mycobacterium tuberculosis complex resistant to first and second-line TB medications. Treatment: She received 5 months of intensive multidrug treatment without sputum smear conversion. She then underwent resection of the diseased lung. The total cost incurred amounted to over S$100,000. Outcome: She achieved sputum smear/culture conversion post-surgery, but will require further medical therapy for at least 18 months. Conclusion: XDR-TB is poorly responsive to therapy and extremely expensive to manage. Its prevention by strict compliance to therapy is paramount. Ann Acad Med Singapore 40;3:132-5
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页码:132 / 135
页数:4
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