Generalized pustular psoriasis (von Zumbusch)

被引：19

作者：

Romiti, Ricardo ^{[1
]}

da Silva Hirayama, Andre Luis ^{[1
]}

Arnone, Marcelo ^{[1
]}

Magalhaes, Renata Ferreira ^{[2
]}

机构：

[1] Univ Sao Paulo, Dept Dermatol, Hosp Clin, Fac Med, Sao Paulo, SP, Brazil

[2] Univ Estadual Campinas, Fac Ciencias Med, Discipline Dermatol, Campinas, SP, Brazil

来源：

ANAIS BRASILEIROS DE DERMATOLOGIA | 2022年 / 97卷 / 01期

关键词：

Acrodermatitis; Psoriasis; Psoriasis/epidemiology; Psoriasis/genetics; Psoriasis/physiopathology; Psoriasis/therapy; IMPETIGO HERPETIFORMIS; CHILDHOOD; SPECTRUM; AGEP;

D O I：

10.1016/j.abd.2021.05.011

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Generalized pustular psoriasis (von Zumbusch) is a rare and acute eruption characterized by multiple sterile pustules over an erythematous and edematous background, eventually associated with psoriasis vulgaris. Classically, it manifests as a potentially severe systemic picture and demands prompt diagnosis and intervention. The duration of each flare-up and intervals between the pustular episodes is extremely variable. Recently, genetic abnormalities have been identified mainly in the familial and early variants of this disease. The therapeutic arsenal is limited; however, new drugs being evaluated aim to control both pustular flare-ups and disease recurrences. (C) 2021 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.

引用

页码：63 / 74

页数：12

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