Generalized pustular psoriasis (von Zumbusch)

被引：19
作者：
Romiti, Ricardo [1 ]
da Silva Hirayama, Andre Luis [1 ]
Arnone, Marcelo [1 ]
Magalhaes, Renata Ferreira [2 ]
机构：
[1] Univ Sao Paulo, Dept Dermatol, Hosp Clin, Fac Med, Sao Paulo, SP, Brazil
[2] Univ Estadual Campinas, Fac Ciencias Med, Discipline Dermatol, Campinas, SP, Brazil
来源：
ANAIS BRASILEIROS DE DERMATOLOGIA | 2022年 / 97卷 / 01期
关键词：
Acrodermatitis; Psoriasis; Psoriasis/epidemiology; Psoriasis/genetics; Psoriasis/physiopathology; Psoriasis/therapy; IMPETIGO HERPETIFORMIS; CHILDHOOD; SPECTRUM; AGEP;
D O I：
10.1016/j.abd.2021.05.011
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Generalized pustular psoriasis (von Zumbusch) is a rare and acute eruption characterized by multiple sterile pustules over an erythematous and edematous background, eventually associated with psoriasis vulgaris. Classically, it manifests as a potentially severe systemic picture and demands prompt diagnosis and intervention. The duration of each flare-up and intervals between the pustular episodes is extremely variable. Recently, genetic abnormalities have been identified mainly in the familial and early variants of this disease. The therapeutic arsenal is limited; however, new drugs being evaluated aim to control both pustular flare-ups and disease recurrences. (C) 2021 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码：63 / 74
页数：12
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