Full-dose ifosfamide can be safely administered to outpatients

被引：11

作者：

Meazza, Cristina ^{[1
]}

Bisogno, Gianni ^{[2
]}

Casanova, Michela ^{[1
]}

Zanetti, Ilaria ^{[2
]}

Carli, Modesto ^{[2
]}

Ferrari, Andrea ^{[1
]}

机构：

[1] Ist Nazl Tumori, Pediat Oncol Unit, I-20133 Milan, MI, Italy

[2] Univ Hosp Padova, Dept Pediat, Div Hematol Oncol, Padua, Italy

来源：

PEDIATRIC BLOOD & CANCER | 2008年 / 50卷 / 02期

关键词：

ifosfamide; outpatient; pediatric soft tissue sarcomas; rhabdomyosarcoma; toxicity;

D O I：

10.1002/pbc.20958

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This report compares a traditional full-dose ifosfamide administration modality (24-hr hyperhydration and mesna infusion) with a simplified 9-hr hyperhydration and mesna infusion for use in Outpatients. Acute ifosfamide toxicity was the same, suggesting that ifosfamide could be safely administered to outpatients, reducing the currently-recommended prolonged hyperhydration and mesna uroprotection, thus resulting in shorter hospital stays and consequently lower costs. Pediatr Blood Cancer 2008;50:375-378. (c) 2006 Wiley-Liss, Inc.

引用

页码：375 / 378

页数：4

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