Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial

被引：66

作者：

Gray, Alasdair J. ^{[1
,2
]}

Roobottom, Carl ^{[3
,4
]}

Smith, Jason E. ^{[3
]}

Goodacre, Steve ^{[5
]}

Oatey, Katherine ^{[1
]}

O'Brien, Rachel ^{[2
]}

Storey, Robert F. ^{[5
]}

Curzen, Nick ^{[6
]}

Keating, Liza ^{[7
]}

Kardos, Attila ^{[8
,9
]}

Felmeden, Dirk ^{[10
]}

Lee, Robert J. ^{[1
]}

Thokala, Praveen ^{[5
]}

Lewis, Steff C. ^{[1
]}

Newby, David E. ^{[1
,2
]}

机构：

[1] Univ Edinburgh, Edinburgh, Midlothian, Scotland

[2] Royal Infirm Edinburgh NHS Trust, NHS Lothian, Edinburgh, Midlothian, Scotland

[3] Univ Hosp Plymouth NHS Trust, Plymouth, Devon, England

[4] Univ Plymouth, Plymouth, Devon, England

[5] Univ Sheffield, Sheffield, S Yorkshire, England

[6] Univ Southampton, Southampton, Hants, England

[7] Royal Berkshire NHS Fdn Trust, Reading, Berks, England

[8] Milton Keynes Univ Hosp NHS Fdn Trust, Milton Keynes, Bucks, England

[9] Univ Buckingham, Buckingham, England

[10] Torbay & South Devon NHS Fdn Trust, Torquay, England

来源：

BMJ-BRITISH MEDICAL JOURNAL | 2021年 / 374卷

关键词：

ACUTE CHEST-PAIN; CT ANGIOGRAPHY; CARE;

D O I：

10.1136/bmj.n2106

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVES To establish if the use of early computed tomography (CT) coronary angiography improves one year clinical outcomes in patients presenting to the emergency department with acute chest pain and at intermediate risk of acute coronary syndrome and subsequent clinical events. DESIGN Randomised controlled trial. SETTING 37 hospitals in the UK. PARTICIPANTS Adults with suspected or a provisional diagnosis of acute coronary syndrome and one or more of previous coronary heart disease, raised levels of cardiac troponin, or abnormal electrocardiogram. INTERVENTIONS Early CT coronary angiography and standard of care compared with standard of care only. MAIN OUTCOME MEASURES Primary endpoint was all cause death or subsequent type 1 or 4b myocardial infarction at one year.

引用

页数：12

共 50 条

[41] Can computed tomography improve outcomes in acute coronary syndrome? [J].

Boxt, Lawrence M. ;

Lipton, Martin J. .

BRITISH JOURNAL OF HOSPITAL MEDICINE, 2009, 70 (08) :459-463

[42] Incremental prognostic value of sequential imaging of single-photon emission computed tomography and coronary computed tomography angiography in patients with suspected coronary artery disease [J].

Kim, Hack-Lyoung ;

Kim, Yong-Jin ;

Lee, Seung-Pyo ;

Park, Eun-Ah ;

Paeng, Jin-Chul ;

Kim, Hyung-Kwan ;

Lee, Whal ;

Cho, Goo-Yeong ;

Zo, Joo-Hee ;

Choi, Dong-Ju ;

Sohn, Dae-Won .

EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, 2014, 15 (08) :878-885

[43] Coronary Computed Tomography Angiography Analysis of Calcium Content to Identify Non-culprit Vulnerable Plaques in Patients With Acute Coronary Syndrome [J].

Pezel, Theo ;

Sideris, Georgios ;

Dillinger, Jean-Guillaume ;

Logeart, Damien ;

Manzo-Silberman, Stephane ;

Cohen-Solal, Alain ;

Beauvais, Florence ;

Devasenapathy, Niveditha ;

Laissy, Jean-Pierre ;

Henry, Patrick .

FRONTIERS IN CARDIOVASCULAR MEDICINE, 2022, 9

[44] Can Coronary Computed Tomography Angiography Replace Invasive Angiography? Coronary Computed Tomography Angiography Cannot Replace Invasive Angiography [J].

Stefanini, Giulio G. ;

Windecker, Stephan .

CIRCULATION, 2015, 131 (04) :418-426

[45] Prevalence and Prognosis of Nonobstructive Coronary Artery Disease in Patients Undergoing Coronary Angiography or Coronary Computed Tomography Angiography: A Meta-Analysis [J].

Wang, Zhi Jian ;

Zhang, Lin Lin ;

Elmariah, Sammy ;

Han, Hong Ya ;

Zhou, Yu Jie .

MAYO CLINIC PROCEEDINGS, 2017, 92 (03) :329-346

[46] Assessment of Coronary Atherosclerosis in Patients With Familial Hypercholesterolemia by Coronary Computed Tomography Angiography [J].

Tada, Hayato ;

Kawashiri, Masa-aki ;

Okada, Hirofumi ;

Teramoto, Ryota ;

Konno, Tetsuo ;

Yoshimuta, Tsuyoshi ;

Sakata, Kenji ;

Nohara, Atsushi ;

Inazu, Akihiro ;

Kobayashi, Junji ;

Mabuchi, Hiroshi ;

Yamagishi, Masakazu ;

Hayashi, Kenshi .

AMERICAN JOURNAL OF CARDIOLOGY, 2015, 115 (06) :724-729

[47] Computed tomography versus invasive coronary angiography: design and methods of the pragmatic randomised multicentre DISCHARGE trial [J].

Napp, Adriane E. ;

Haase, Robert ;

Laule, Michael ;

Schuetz, Georg M. ;

Rief, Matthias ;

Dreger, Henryk ;

Feuchtner, Gudrun ;

Friedrich, Guy ;

Spacek, Miloslav ;

Suchanek, Vojtech ;

Kofoed, Klaus Fuglsang ;

Engstroem, Thomas ;

Schroeder, Stephen ;

Drosch, Tanja ;

Gutberlet, Matthias ;

Woinke, Michael ;

Maurovich-Horvat, Pal ;

Merkely, Bela ;

Donnelly, Patrick ;

Ball, Peter ;

Dodd, Jonathan D. ;

Quinn, Martin ;

Saba, Luca ;

Porcu, Maurizio ;

Francone, Marco ;

Mancone, Massimo ;

Erglis, Andrejs ;

Zvaigzne, Ligita ;

Jankauskas, Antanas ;

Sakalyte, Gintare ;

Haran, Tomasz ;

Ilnicka-Suckiel, Malgorzata ;

Bettencourt, Nuno ;

Gama-Ribeiro, Vasco ;

Condrea, Sebastian ;

Benedek, Imre ;

Adjic, Nada Cemerlic ;

Adjic, Oto ;

Rodriguez-Palomares, Jose ;

del Blanco, Bruno Garcia ;

Roditi, Giles ;

Berry, Colin ;

Davis, Gershan ;

Thwaite, Erica ;

Knuuti, Juhani ;

Pietila, Mikko ;

Kepka, Cezary ;

Kruk, Mariusz ;

Vidakovic, Radosav ;

Neskovic, Aleksandar N. .

EUROPEAN RADIOLOGY, 2017, 27 (07) :2957-2968

[48] Coronary Computed Tomography Angiography in the Evaluation of Chest Pain of Suspected Cardiac Origin [J].

Bittencourt, Marcio Sommer ;

Hulten, Edward A. ;

Veeranna, Vikas ;

Blankstein, Ron .

CIRCULATION, 2016, 133 (20) :1963-1968

[49] Assessing suspected angina: requiem for coronary computed tomography angiography or exercise electrocardiogram? [J].

Vrints, Christiaan J. M. ;

Senior, Roxy ;

Crea, Filippo ;

Sechtem, Udo .

EUROPEAN HEART JOURNAL, 2017, 38 (23) :1792-1800

[50] 10-Year Follow-Up After Coronary Computed Tomography Angiography in Patients With Suspected Coronary Artery Disease [J].

Finck, Tom ;

Hardenberg, Julius ;

Will, Albrecht ;

Hendrich, Eva ;

Haller, Bernhard ;

Martinoff, Stefan ;

Hausleiter, Joerg ;

Hadamitzky, Martin .

JACC-CARDIOVASCULAR IMAGING, 2019, 12 (07) :1330-1338

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