Early computed tomography coronary angiography in patients with suspected acute coronary syndrome: randomised controlled trial

OBJECTIVES To establish if the use of early computed tomography (CT) coronary angiography improves one year clinical outcomes in patients presenting to the emergency department with acute chest pain and at intermediate risk of acute coronary syndrome and subsequent clinical events. DESIGN Randomised controlled trial. SETTING 37 hospitals in the UK. PARTICIPANTS Adults with suspected or a provisional diagnosis of acute coronary syndrome and one or more of previous coronary heart disease, raised levels of cardiac troponin, or abnormal electrocardiogram. INTERVENTIONS Early CT coronary angiography and standard of care compared with standard of care only. MAIN OUTCOME MEASURES Primary endpoint was all cause death or subsequent type 1 or 4b myocardial infarction at one year.