Preliminary evidence of widespread morphological variations of the brain in dyslexia

被引：157

作者：

Brown, WE

Eliez, S

Menon, V

Rumsey, JM

White, CD

Reiss, AL

机构：

[1] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford Psychiat Neuroimaging Lab, Stanford, CA 94305 USA

[2] NIMH, Clin Neurosci Branch, Rockville, MD 20857 USA

来源：

NEUROLOGY | 2001年 / 56卷 / 06期

关键词：

D O I：

10.1212/WNL.56.6.781

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The MR images of 16 men with dyslexia and 14 control subjects were compared using a voxel-based analysis. Evidence of decreases in gray matter in dyslexic subjects, most notably in the left temporal lobe and bilaterally in the temporoparietooccipital juncture, but also in the frontal lobe, caudate, thalamus, and cerebellum, was found. Widely distributed morphologic differences affecting several brain regions may contribute to the deficits associated with dyslexia.

引用

页码：781 / 783

页数：3

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