Prophylaxis and treatment of chronic synovitis in haemophilia patients with inhibitors

被引:7
作者
Rodriguez-Merchan, E. C.
Valentino, L.
Quintana, M.
机构
[1] La Paz Univ Hosp, Dept Orthopaed, Madrid, Spain
[2] La Paz Univ Hosp, Haemophilia Unit, Madrid, Spain
[3] Rush Presbyterian St Lukes Med Ctr, Dept Haematol, Chicago, IL 60612 USA
[4] La Paz Univ Hosp, Dept Haematol, Madrid, Spain
关键词
haemophilia; inhibitors; prophylaxis; radiactive synoviorthesis; synovitis;
D O I
10.1111/j.1365-2516.2007.01540.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Prophylaxis is paramount to try to avoid the development of haemophilic synovitis. The best treatment for synovitis in patients with inhibitors is radioactive synoviorthesis (rhenium for ankle and elbows, yttrium for knees). With both methods (prohylaxis and radioactive synoviorthesis), we can delay the development of severe haemophilic arthropathy, that eventually will require major orthopaedic surgery.
引用
收藏
页码:45 / 48
页数:4
相关论文
共 50 条
[21]   Guidelines for the management of acute joint bleeds and chronic synovitis in haemophilia [J].
Hanley, J. ;
McKernan, A. ;
Creagh, M. D. ;
Classey, S. ;
McLaughlin, P. ;
Goddard, N. ;
Briggs, P. J. ;
Frostick, S. ;
Giangrande, P. ;
Wilde, J. ;
Thachil, J. ;
Chowdary, P. .
HAEMOPHILIA, 2017, 23 (04) :511-520
[22]   Synovitis and synovectomy in haemophilia [J].
van Vulpen, Lize F. D. ;
Thomas, Sylvia ;
Keny, Swapnil A. ;
Mohanty, Shubhranshu S. .
HAEMOPHILIA, 2021, 27 :96-102
[23]   Considerations in individualizing prophylaxis in patients with haemophilia A [J].
Valentino, L. A. .
HAEMOPHILIA, 2014, 20 (05) :607-615
[24]   Prophylaxis or on demand treatment for adult patients with severe haemophilia? [J].
Neme, Daniela ;
Del Rio, Lina ;
Cocca, Andrea ;
Chirino, Walter .
HAEMOPHILIA, 2023, 29 :12-13
[25]   Immune tolerance treatment in haemophilia patients with inhibitors:: the Spanish Registry [J].
Haya, S ;
López, MF ;
Aznar, JA ;
Batlle, J .
HAEMOPHILIA, 2001, 7 (02) :154-159
[26]   Randomized comparison of prophylaxis and on-demand regimens with FEIBA NF in the treatment of haemophilia A and B with inhibitors [J].
Antunes, S. V. ;
Tangada, S. ;
Stasyshyn, O. ;
Mamonov, V. ;
Phillips, J. ;
Guzman-Becerra, N. ;
Grigorian, A. ;
Ewenstein, B. ;
Wong, W. -Y. .
HAEMOPHILIA, 2014, 20 (01) :65-72
[27]   Prevention of haemophilic synovitis: prophylaxis [J].
Lee, C. A. .
HAEMOPHILIA, 2007, 13 :20-25
[28]   The burden of inhibitors in haemophilia patients [J].
Walshl, Christopher E. ;
Jimenez-Yuste, Victor ;
Auerswald, Guenter ;
Grancha, Salvador .
THROMBOSIS AND HAEMOSTASIS, 2016, 116 :S10-S17
[29]   Prophylaxis in children with haemophilia in an evolving treatment landscape [J].
Mancuso, Maria Elisa ;
Male, Christoph ;
Kenet, Gili ;
Kavakli, Kaan ;
Koenigs, Christoph ;
Blatny, Jan ;
Fijnvandraat, Karin .
HAEMOPHILIA, 2021, 27 (06) :889-896
[30]   Experience of prophylaxis treatment in children with severe haemophilia [J].
Yee, TT ;
Beeton, K ;
Griffioen, A ;
Harrington, C ;
Miners, A ;
Lee, CA ;
Brown, SA .
HAEMOPHILIA, 2002, 8 (02) :76-82