Tandem Incorporation of Enantiomeric Residues Engenders Discrete Peptoid Structures

被引：14

作者：

Gorske, Benjamin C. ^{[1
]}

Mumford, Emily M. ^{[1
]}

Conry, Rebecca R. ^{[2
]}

机构：

[1] Bowdoin Coll, Dept Chem, 6600 Coll Stn, Brunswick, ME 04011 USA

[2] Colby Coll, Dept Chem, 5750 Mayflower Hill, Waterville, ME 04901 USA

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 11期

关键词：

SECONDARY-STRUCTURE; SIDE-CHAINS; FOLDAMERS; HELICES; DIVERSITY; GLYCINES); OLIGOMERS; DESIGN; FAMILY;

D O I：

10.1021/acs.orglett.6b01283

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new peptoid design strategy entailing the concurrent inclusion of enantiomeric side chains enabled the construction of several new structural motifs, including a newly characterized "omega-strand". This new architectural technique significantly expands peptoid structural and functional space and can potentially be applied to other foldameric systems.

引用

页码：2780 / 2783

页数：4

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