Using salvage Boron Neutron Capture Therapy (BNCT) for recurrent malignant brain tumors in Taiwan

被引:32
作者
Lan, Tien-Li [1 ]
Chou, Fong-In [2 ]
Lin, Ko-Han [3 ]
Pan, Po-Shen [4 ]
Lee, Jia-Cheng [1 ]
Huang, Wen-Sheng [3 ]
Liu, Yu-Ming [1 ]
Chao, Yee [5 ]
Chen, Yi-Wei [1 ]
机构
[1] Taipei Vet Gen Hosp, Dept Oncol, Div Radiotherapy, Taipei, Taiwan
[2] Natl Tsing Hua Univ, Nucl Sci & Technol Dev Dept, Hsinchu, Taiwan
[3] Taipei Vet Gen Hosp, Dept Nucl Med, Taipei, Taiwan
[4] Tamkang Univ, Dept Chem, New Taipei, Taiwan
[5] Natl Yang Ming Univ, Taipei Vet Gen Hosp, Dept Oncol, Taipei, Taiwan
关键词
Boron Neutron Capture Therapy; Recurrent glioblastoma; Mismatch repair syndrome;
D O I
10.1016/j.apradiso.2020.109105
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Radiation therapy has an irreplaceable role in modern oncologic therapy, thanks to the advanced radiation techniques developed in recent decades. However, photon-resistant cases are sometimes encountered. Boron Neutron Capture Therapy (BNCT) is a highly selective radiotherapy technique due to the high tumor to tissue ratio of boronophenylalanine (BPA), the unique medication used for the BNCT treatment reaction. In this study, we report on three special patients with malignant brain tumors treated with BNCT.
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页数:6
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