Metabolic remodeling of human skin fibroblasts as model for studying mitochondrial diseases and drug-induced toxicity

被引:0
|
作者
Pereira, S. P. [1 ,2 ]
Serafim, T. L. [1 ]
Cunha-Oliveira, T. [1 ]
Deus, C. M. [1 ,2 ]
Starostina, I. G. [3 ]
Ivanova, V. V. [3 ]
Rizvanov, A. A. [3 ]
Oliveira, P. J. [1 ]
机构
[1] Univ Coimbra, CNC Ctr Neurosci & Cell Biol, P-3004517 Coimbra, Portugal
[2] Univ Coimbra, Sch Sci & Technol, Dept Life Sci, P-3004517 Coimbra, Portugal
[3] Kazan Fed Univ, Inst Fundamental Med & Biol, Kazan 420008, Russia
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
5.40
引用
收藏
页码:66 / 66
页数:1
相关论文
共 50 条
  • [22] INTRODUCTION TO BASIC MITOCHONDRIAL BIOLOGY AS IT RELATES TO DRUG-INDUCED TOXICITY
    Dykens, James
    DRUG METABOLISM AND PHARMACOKINETICS, 2018, 33 (01) : S12 - S12
  • [23] Mitochondrial remodeling in human skin fibroblasts from sporadic male Parkinson's disease patients uncovers metabolic and mitochondrial bioenergetic defects
    Deus, Claudia M.
    Pereira, Susana P.
    Cunha-Oliveira, Teresa
    Pereira, Francisco B.
    Raimundo, Nuno
    Oliveira, Paulo J.
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2020, 1866 (03):
  • [24] Establishment of a HepG2 cell culture model for detection of drug-induced mitochondrial toxicity
    Hoeschele, Doris
    Wiertz, Martina
    Moreno, Inmaculada Garcia
    TOXICOLOGY LETTERS, 2007, 172 : S79 - S80
  • [25] Role of Human Orphan Esterases in Drug-induced Toxicity
    Fukami, Tatsuki
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 2015, 135 (11): : 1235 - 1244
  • [26] Zebrafish: a predictive model for assessing drug-induced toxicity
    McGrath, Patricia
    Li, Chun-Qi
    DRUG DISCOVERY TODAY, 2008, 13 (9-10) : 394 - 401
  • [27] Mitochondrial and metabolic remodelling in human skin fibroblasts in response to glucose availability
    Pinho, Sonia A.
    Costa, Claudio F.
    Deus, Claudia M.
    Pinho, Sonia L. C.
    Miranda-Santos, Ines
    Afonso, Goncalo
    Bagshaw, Olivia
    Stuart, Jeffrey A.
    Oliveira, Paulo J.
    Cunha-Oliveira, Teresa
    FEBS JOURNAL, 2022, 289 (17) : 5198 - 5217
  • [28] Bioenergetic profile and drug-induced toxicity response of a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms
    Pereira, C. V.
    Oliveira, P. J.
    Will, Y.
    Nadanaciva, S.
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2013, 43 : 48 - 48
  • [29] Mechanistic understanding of drug-induced mitochondrial toxicity using isolated mitochondrial complex assays
    Low, Emma L.
    Burnham, Matthew
    Garside, Helen
    Valentin, Jean-Pierre
    Bowes, Joanne
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2012, 66 (02) : 165 - 165
  • [30] Drug-induced mitochondrial toxicity: Risks of developing glucose handling impairments
    Kuretu, Auxiliare
    Arineitwe, Charles
    Mothibe, Mamosheledi
    Ngubane, Phikelelani
    Khathi, Andile
    Sibiya, Ntethelelo
    FRONTIERS IN ENDOCRINOLOGY, 2023, 14