Anti-MuSK myasthenia gravis presenting with Epstein-Barr virus-associated mononucleosis and immune-mediated diabetes mellitus

被引:11
作者
Bhibhatbhan, Arunee
Kline, Gregory
Vincent, Angela
Toth, Cory
机构
[1] Univ Calgary, Dept Clin Neurosci, Calgary, AB T2N 4N1, Canada
[2] Univ Calgary, Dept Med, Calgary, AB, Canada
[3] Calgary Hlth Reg, Calgary, AB, Canada
[4] Weatherall Inst Mol Med, Dept Clin Neurol, Neurosci Grp, Oxford, England
关键词
diabetes mellitus; Epstein-Barr virus; muscle-specific kinase; myasthenia gravis;
D O I
10.1002/mus.20746
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a young woman with the abrupt onset of infectious mononucleosis due to Epstein-Barr virus associated with a subsequent autoimmune form of diabetes mellitus and myasthenia gravis with anti-muscle-specific kinase (MuSK) antibodies. The simultaneous onset of these two autoimmune diseases preceded by a systemic viral illness supports a causal relationship between MuSK antibodies and myasthenia gravis and suggests the possibility of a viral trigger in some cases.
引用
收藏
页码:264 / 266
页数:3
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