Preparation of Alginate Micro-Gel by High Pressure Water Method

被引：0
|
作者：
Murata, Yoshifumi [1 ]
Suzuki, Yasuyuki [1 ]
Isobe, Takashi [1 ]
Kofuji, Kyoko [1 ]
Kawashima, Susumu [1 ]
机构：
[1] Hokuriku Univ, Fac Pharmaceut Sci, Kanazawa, Ishikawa 9201181, Japan
来源：
KOBUNSHI RONBUNSHU | 2010年 / 67卷 / 09期
关键词：
Alginate Micro-Gel; High Pressure Water; Hydrocortisone; Dissolution Profile; BEADS;
D O I：
10.1295/koron.67.549
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Alginate micro-gel (AMG) containing a model compound, hydrocortisone (HC), was prepared by high pressure water method. The release profile of HC from AMG was then investigated. The mean particle size of AMG was less than 100 mu m: the size was controllable by the pressure of water. HC incorporated in AMG was immediately dissolved in physiological saline; the dissolution profile was reproducible. These results suggest that AMG is potentially useful to improve the solubility of water-insoluble compounds.
引用
收藏
页码：549 / 552
页数：4
相关论文
共 50 条
  • [31] A sensitive standardised micro-gel well diffusion assay for the determination of antimicrobial activity
    du Toit, EA
    Rautenbach, M
    JOURNAL OF MICROBIOLOGICAL METHODS, 2000, 42 (02) : 159 - 165
  • [32] Micro-gel thin film molecularly imprinted polymer coating for extraction of organophosphorus pesticides from water and beverage samples
    Azizi, Ali
    Shahhoseini, Fereshteh
    Langille, Evan A.
    Akhoondi, Reza
    Bottaro, Christina S.
    Analytica Chimica Acta, 2021, 1187
  • [33] Micro-gel thin film molecularly imprinted polymer coating for extraction of organophosphorus pesticides from water and beverage samples
    Azizi, Ali
    Shahhoseini, Fereshteh
    Langille, Evan A.
    Akhoondi, Reza
    Bottaro, Christina S.
    ANALYTICA CHIMICA ACTA, 2021, 1187
  • [34] Fabrication of Micro-Gel Robot Having a Soft-Rigid Hybrid Structure
    Watanabe, Tomoki
    Yokoyama, Yoshiyuki
    Hayakawa, Takeshi
    2018 INTERNATIONAL SYMPOSIUM ON MICRO-NANOMECHATRONICS AND HUMAN SCIENCE (MHS), 2018,
  • [35] Micro-Gel Ensembles for Accelerated Healing of Chronic Wound via pH Regulation
    Cui, Tingting
    Yu, Jiafei
    Wang, Cai-Feng
    Chen, Su
    Li, Qing
    Guo, Kun
    Qing, Renkun
    Wang, Gefei
    Ren, Jianan
    ADVANCED SCIENCE, 2022, 9 (22)
  • [36] Effect of micro-gel shape and concentration on sensory perception of micro-gels-enriched stirred yoghurts
    Rohart, Anne
    Sieffermann, Jean-Marc
    Michon, Camille
    COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2015, 475 : 94 - 102
  • [37] Preparation, characterization of curdlan-based emulsion micro-gel particles and its application in low-fat pork sausages
    Zhang, Xirui
    Guo, Yaxian
    Liu, Hong
    Liang, Bin
    He, Hongjun
    Fu, Xuejun
    Sun, Chanchan
    Li, Xiulian
    Ji, Changjian
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2023, 185
  • [38] Preparation of YVO4:Eu3+ phosphors via micro-gel spray freeze-drying process
    Iwamura, Masayuki
    Petrykin, Valery
    Kakihana, Masato
    JOURNAL OF THE CERAMIC SOCIETY OF JAPAN, 2007, 115 (1348) : 920 - 924
  • [39] HIGH-RESOLUTION MICRO-GEL SYSTEM FOR ANALYZING SMALL AMOUNTS OF PROTEIN WITH A WIDE DIVERSITY OF MOLECULAR-WEIGHTS
    SHAW, PH
    HENNEN, S
    MICROCHEMICAL JOURNAL, 1975, 20 (02) : 183 - 189
  • [40] Production of hemoglobin-containing micro-gel beads as oxygen carriers for cell culture
    Takeda, T.
    Iwanaga, S.
    Saito, N.
    Nakamura, M.
    JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 2012, 6 : 274 - 274
12345