[1] Univ Fed Pernambuco, Dept Genet, Recife, PE, Brazil
[2] CPqAM FIOCRUZ Pernambuco, Aggeu Magalhaes Res Ctr, Dept Immunol, Recife, PE, Brazil
[3] Univ Fed Pernambuco, LIKA, Recife, PE, Brazil
[4] Univ Fed Pernambuco, Dept Pathol, Recife, PE, Brazil
[5] Inst Maternal & Child Hlth, IRCCS Burlo Garofolo, Trieste, Italy