Autoaggression syndrome resembling acute graft-versus-host disease grade IV after autologous peripheral blood stem cell transplantation for breast cancer

被引:8
作者
de Arriba, F [1 ]
Corral, J [1 ]
Ayala, F [1 ]
Heras, I [1 ]
Moraleda, JM [1 ]
Osma, MM [1 ]
González-Conejero, R [1 ]
Ortuño, F [1 ]
Vicente, V [1 ]
机构
[1] Hosp Gen Univ, Sch Med, Unit Oncohematol & Hemotherapy, Murcia, Spain
关键词
GVHD; autologous transplantation; breast cancer;
D O I
10.1038/sj.bmt.1701619
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Acute graft-versus-host disease (aGVHD) after autologous progenitor cell transplantation has been associated with blood transfusion or cyclosporine. Mild aGVHD grades I-II, identified as autoaggression or engraftment syndrome, has recently been described in autologous progenitor transplantation. Here, we report the first case of pathologically documented grade IV aGVHD after autologous peripheral blood progenitor cell transplantation in a patient with breast cancer, The allogeneic origin was excluded by molecular techniques, and no cyclosporine or cytokines were administered.
引用
收藏
页码:621 / 624
页数:4
相关论文
共 13 条
[1]  
ANDERSON KC, 1990, NEW ENGL J MED, V323, P315
[2]   A PHASE-II STUDY OF HIGH-DOSE CYCLOPHOSPHAMIDE, THIOTEPA, AND CARBOPLATIN WITH AUTOLOGOUS MARROW SUPPORT IN WOMEN WITH MEASURABLE ADVANCED BREAST-CANCER RESPONDING TO STANDARD-DOSE THERAPY [J].
ANTMAN, K ;
AYASH, L ;
ELIAS, A ;
WHEELER, C ;
HUNT, M ;
EDER, JP ;
TEICHER, BA ;
CRITCHLOW, J ;
BIBBO, J ;
SCHNIPPER, LE ;
FREI, E .
JOURNAL OF CLINICAL ONCOLOGY, 1992, 10 (01) :102-110
[3]  
APPLETON AL, 1993, BONE MARROW TRANSPL, V11, P349
[4]  
DROBYSKI W, 1989, BLOOD, V74, P2285
[5]  
ESTEBAN JM, 1995, MODERN PATHOL, V8, P59
[6]   PHASE-I TRIAL OF INTERFERON-GAMMA TO POTENTIATE CYCLOSPORINE-INDUCED GRAFT-VERSUS-HOST DISEASE IN WOMEN UNDERGOING AUTOLOGOUS BONE-MARROW TRANSPLANTATION FOR BREAST-CANCER [J].
KENNEDY, MJ ;
VOGELSANG, GB ;
JONES, RJ ;
FARMER, ER ;
HESS, AD ;
ALTOMONTE, V ;
HUELSKAMP, AM ;
DAVIDSON, NE .
JOURNAL OF CLINICAL ONCOLOGY, 1994, 12 (02) :249-257
[7]  
LEE CK, 1995, BONE MARROW TRANSPL, V16, P175
[8]   Increased frequency of autoaggression syndrome associated with autologous stem cell transplantation in breast cancer patients [J].
Moreb, JS ;
Kubilis, PS ;
Mullins, DL ;
Myers, L ;
Youngblood, M ;
Hutcheson, C .
BONE MARROW TRANSPLANTATION, 1997, 19 (02) :101-106
[9]  
Pati AR, 1996, BONE MARROW TRANSPL, V17, P1081
[10]  
Rainey MG, 1996, BONE MARROW TRANSPL, V17, P1077