Harmful Impact of Tobacco Smoking and Alcohol Consumption on the Atrial Myocardium

被引:11
作者
Ohlrogge, Amelie H. [1 ,2 ]
Frost, Lars [3 ,4 ]
Schnabel, Renate B. [1 ,2 ]
机构
[1] Univ Heart & Vasc Ctr Hamburg, Dept Cardiol, D-20246 Hamburg, Germany
[2] German Ctr Cardiovasc Res DZHK, Partner Site Hamburg Kiel Lubeck, D-20246 Hamburg, Germany
[3] Univ Clin Dev Innovat Patient Pathways, Silkeborg Reg Hosp, Diagnost Ctr, DK-8600 Silkeborg, Denmark
[4] Aarhus Univ, Dept Clin Med, DK-8200 Aarhus, Denmark
基金
欧洲研究理事会;
关键词
atria; atrial myocardium; atrial cardiomyopathy; tobacco; cigarettes; smoking; alcohol; drinking; HEART-RATE-VARIABILITY; AMBULATORY BLOOD-PRESSURE; CHRONIC CIGARETTE-SMOKING; DEEP TERMINAL NEGATIVITY; RISK-FACTOR; OXIDATIVE STRESS; ISCHEMIC-STROKE; P-WAVE; ATHEROSCLEROSIS-RISK; MAGNETIC-RESONANCE;
D O I
10.3390/cells11162576
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tobacco smoking and alcohol consumption are widespread exposures that are legal and socially accepted in many societies. Both have been widely recognized as important risk factors for diseases in all vital organ systems including cardiovascular diseases, and with clinical manifestations that are associated with atrial dysfunction, so-called atrial cardiomyopathy, especially atrial fibrillation and stroke. The pathogenesis of atrial cardiomyopathy, atrial fibrillation, and stroke in context with smoking and alcohol consumption is complex and multifactorial, involving pathophysiological mechanisms, environmental, and societal aspects. This narrative review summarizes the current literature regarding alterations in the atrial myocardium that is associated with smoking and alcohol.
引用
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页数:29
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