Water soluble 1,8-naphthalimide fluorescent pH probes and their application to bioimagings

被引：45

作者：

Xie, Jian ^{[1
]}

Chen, Yuhua ^{[2
]}

Yang, Wen ^{[1
]}

Xu, Dongmei ^{[1
]}

Zhang, Keda ^{[1
]}

机构：

[1] Soochow Univ, Natl Engn Lab Modern Silk, Jiangsu Key Lab Adv Funct Polymer Design & Applic, Key Lab Organ Synth Jiangsu Prov,Coll Chem Chem E, Suzhou 215123, Peoples R China

[2] Soochow Univ, Coll Preclin Med & Biol Sci, Suzhou 215123, Peoples R China

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 2011年 / 223卷 / 2-3期

基金：

中国国家自然科学基金;

关键词：

Naphthalimide; Fluorescence; Probe; Proton; Bioimaging; PHOTOINDUCED ELECTRON-TRANSFER; TRANSITION-METAL IONS; LARGE RED-SHIFT; SENSORS; DESIGN; GREEN; CHEMOSENSOR; DERIVATIVES; DYES; EMISSION;

D O I：

10.1016/j.jphotochem.2011.08.006

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Two water soluble and high selective 1.8-naphthalimide fluorescent probes for protons have been synthesized by simple and efficient one-step reaction under very mild conditions. Their photophysical characteristics in Britton-Robinson buffer have been studied. All detections were carried out in aqueous media and a large number of biologically relevant ions showed no obvious interferences with the detection. Fluorescent imaging of living cells treated with the probe in different pH media indicated that the probe could provide extracelluar pH information by the cell's fluorescence. (C) 2011 Elsevier B.V. All rights reserved.

引用

页码：111 / 118

页数：8

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