High dose chemotherapy and autologous stem cell transplantation for metastatic breast cancer: is there a place?

被引：0
|
作者：
Stadtmauer, EA [1 ]
机构：
[1] Univ Penn, Ctr Canc, Bone Marrow & Stem Cell Transplant Program, Philadelphia, PA 19104 USA
来源：
BREAST CANCER RESEARCH AND TREATMENT | 2003年 / 81卷
关键词：
high dose chemotherapy; metastatic breast cancer; stem cell transplant;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Seven comparative trials with over 2000 patients enrolled show no definitive evidence that high dose chemotherapy with stem cell support offers a survival advantage for metastatic breast cancer over conventional dose chemotherapy. Though numbers are low and small differences may exist particularly in subsets of patients, the duration of follow-up is adequate to make the likelihood of a late benefit low. High dose chemotherapy with stem cell transplantation does not have a place in the treatment of metastatic breast cancer outside of clinical trials.
引用
收藏
页码：S111 / S115
页数：5
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