Putting the fizz into chemistry: applications of supercritical carbon dioxide in tissue engineering, drug delivery and synthesis of novel block copolymers

被引：50
作者：
Tai, H.
Popov, V. K.
Shakesheff, K. M.
Howdle, S. M.
机构：
[1] Univ Nottingham, Sch Chem, Clean Technol Grp, Nottingham NG7 2RD, England
[2] Univ Nottingham, Sch Pharm, Adv Drug Delivery & Tissue Engn Grp, Nottingham NG7 2RD, England
[3] Russian Acad Sci, Inst Laser & Informat Technol, Troitsk 142092, Moscow Region, Russia
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 2007年 / 35卷
基金：
英国惠康基金;
关键词：
block copolymer; drug delivery; polymer composite; protein growth factor; supercritical fluid; tissue engineering;
D O I：
10.1042/BST0350516
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This paper describes the recent progress at Nottingham towards the exploitation of the unique properties Of scCO(2) (supercritical carbon dioxide) for the preparation of polymeric scaffolds for tissue engineering applications and new devices for controlled drug delivery, as well as the synthesis of novel block copolymers by the combination of eROP (enzymatic ring opening polymerization) and controlled polymerization methods for the potential use as drug carriers.
引用
收藏
页码：516 / 521
页数：6
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