Controversial aspects of rectal cancer surgery following preoperative chemoradiation

被引：4

作者：

Artioukh, D. Y. ^{[1
]}

机构：

[1] Southport & Ormskirk Hosp, Dept Surg, Southport PR8 6PN, Merseyside, England

来源：

COLORECTAL DISEASE | 2010年 / 12卷

关键词：

Rectal adenocarcinoma; surgery; preoperative chemoradiotherapy; PATHOLOGICAL COMPLETE RESPONSE; COMBINED-MODALITY THERAPY; TOTAL MESORECTAL EXCISION; LOCAL RECURRENCE; ABDOMINOPERINEAL EXCISION; SPHINCTER PRESERVATION; TUMOR-REGRESSION; RADIOTHERAPY; CHEMORADIOTHERAPY; INVOLVEMENT;

D O I：

10.1111/j.1463-1318.2010.02321.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The role of surgery in the loco-regional control of adenocarcinoma of the rectum is being increasingly challenged by the good response rates of neoadjuvant oncological treatment. This review represents an opinion paper outlining well-established choices and new trends in surgical intervention, unresolved difficulties of local and regional staging of rectal malignancy and accurate assessment of tumour response to preoperative downstaging chemoradiation. The influence of preoperative chemoradiation on subsequent surgical strategy is discussed highlighting several controversial aspects of surgical management both when the tumour fails to respond and appears to be irresectable and when complete clinical response is observed.

引用

页码：25 / 29

页数：5

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