Reductive pinacol coupling of aromatic carbonyl compounds catalytic in chromium(II)

被引：0

作者：

Svatos, A ^{[1
]}

Boland, W ^{[1
]}

机构：

[1] Max Planck Inst Chem Ecol, D-07745 Jena, Germany

来源：

SYNLETT | 1998年 / 05期

关键词：

single-electron reduction; additive; silyloxy radical; stereocontrol; chromium(II) catalysis; pinacol coupling;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reductive coupling of aromatic and heteroaromatic aldehydes and ketones bearing different functional groups to pinacols is effectively catalysed with 1-5 mol % of Cr(II) salts or chromocene in THF/DMF mixtures in the presence of manganese powder and trialkyl chlorosilanes. Excellent dl selectivity can be achieved albeit with lower yield using trialkylsilyl chlorides with bulky substituents.

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页码：549 / +

页数：4

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