The effect of dexamethasone on postoperative vomiting and oral intake after adenotonsillectomy

被引:21
作者
Fazel, M. R.
Yegane-Moghaddam, A.
Forghani, Z.
Aghadoost, D.
Mahdian, M.
Fakharian, E.
机构
[1] Kashan Univ Med Sci, Sch Med, Dept ENT, Kashan, Iran
[2] Kashan Univ Med Sci, Sch Med, Dept Anesthesiol, Kashan, Iran
[3] Kashan Univ Med Sci, Sch Med, Dept Ophthalmol, Kashan, Iran
[4] Kashan Univ Med Sci, Sch Med, Dept Surg, Kashan, Iran
关键词
adenotoncillectomy; dexamethasone; vomiting; oral intake;
D O I
10.1016/j.ijporl.2007.04.015
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: Vomiting is one of the most important postoperative complications of adenotonsillectomy. This study was designed to determine the effectiveness of preoperative intravenous dexamethasone on postoperative emesis. Methods: In a double-blind, placebo-controtted clinical trial, 100 patients aged 5-15 years, ASA classes I and II were randomly selected to receive either 0.5 mg/kg IV dexamethasone (n = 50), as study group or an equivalent volume of saline preoperatively, as control group. The anesthetic regimen and surgical procedures were standardized for all patients. The incidence of early and late vomiting, the time to first oral intake and duration of intravenous hydration were compared in both groups. Results: Data analysis showed that the overall incidence of early and late vomiting was significantly lesser in dexamehasone group than the control one. The time to first oral intake and duration of IV therapy were also significantly shorter in dexamethasone group. Conclusion: A single dose of dexamethasone significantly decreased the incidence of postoperative vomiting in early and late recovery phase and shortened the time to first oral intake and the duration of IV therapy. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:1235 / 1238
页数:4
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