Allosteric modulation of human P2X7 receptor by clemastine

被引：0
|
作者：
Schaefer, Michael [1 ]
Hempel, Christoph [1 ]
Urban, Nicole [1 ]
Sobottka, Helga [1 ]
Noerenberg, Wolfgang [1 ]
机构：
[1] Univ Leipzig, Rudolf Boehm Inst Pharmacol & Toxicol, Leipzig, Germany
来源：
PURINERGIC SIGNALLING | 2010年 / 6卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：49 / 49
页数：1
相关论文
共 50 条
  • [21] Calcium-dependent block of P2X7 receptor channel function is allosteric
    Yan, Zonghe
    Khadra, Anmar
    Sherman, Arthur
    Stojilkovic, Stanko S.
    JOURNAL OF GENERAL PHYSIOLOGY, 2011, 138 (04): : 437 - 452
  • [22] Roles of P2X7 Receptor in Glial and Neuroblastoma Cells: The Therapeutic Potential of P2X7 Receptor Antagonists
    Synthia H. Sun
    Molecular Neurobiology, 2010, 41 : 351 - 355
  • [23] Roles of P2X7 Receptor in Glial and Neuroblastoma Cells: The Therapeutic Potential of P2X7 Receptor Antagonists
    Sun, Synthia H.
    MOLECULAR NEUROBIOLOGY, 2010, 41 (2-3) : 351 - 355
  • [24] Modulation of P2X7 receptor activity in experimental autoimmune encephalomyelitis models
    Guillou, C.
    Fourny, M.
    Abad, C.
    Adriouch, S.
    Tan, Y. -V.
    MULTIPLE SCLEROSIS JOURNAL, 2022, 28 (3_SUPPL) : 996 - 996
  • [25] Modulation of P2X7 receptor activity in experimental autoimmune encephalomyelitis models
    Guillou, Charlotte
    Fourny, Marie
    Demeules, Melanie
    Abad, Catalina
    Adriouch, Sahil
    Tan, Yossan Var
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2021, 51 : 275 - 275
  • [26] The P2X7 carboxyl tail is a regulatory module of P2X7 receptor channel activity
    Becker, Daniel
    Woltersdorf, Ronja
    Boldt, Wolfgang
    Schmitz, Stephan
    Braam, Ursula
    Schmalzing, Gurnther
    Markwardt, Fritz
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (37) : 25725 - 25734
  • [27] Targeting the P2X7 receptor in rheumatoid arthritis: biological rationale for P2X7 antagonism
    McInnes, I. B.
    Cruwys, S.
    Bowers, K.
    Braddock, M.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2014, 32 (06) : 878 - 882
  • [28] The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor
    Hempel, Christoph
    Noerenberg, Wolfgang
    Sobottka, Helga
    Urban, Nicole
    Nicke, Annette
    Fischer, Wolfgang
    Schaefer, Michael
    NEUROPHARMACOLOGY, 2013, 75 : 365 - 379
  • [29] Gene structure and chromosomal localization of the human P2X7 receptor
    Buell, GN
    Talabot, F
    Gos, A
    Lorenz, J
    Lai, E
    Morris, MA
    Antonarakis, SE
    RECEPTORS & CHANNELS, 1998, 5 (06): : 347 - +
  • [30] Pharmacokinetic and pharmacodynamic profiling of a P2X7 receptor allosteric modulator GSK1482160 in healthy human subjects
    Ali, Zahid
    Laurijssens, Bart
    Ostenfeld, Thor
    McHugh, Simon
    Stylianou, Anastasia
    Scott-Stevens, Paul
    Hosking, Louise
    Dewit, Odile
    Richardson, Jill C.
    Chen, Chao
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 75 (01) : 197 - 207
12345