Evaluation of the dose perturbation around gold and steel fiducial markers in a medical linac through Geant4 Monte Carlo simulation

被引:5
作者
Pontoriero, Antonio [1 ,2 ]
Amato, Ernesto [1 ]
Iati, Giuseppe [2 ]
De Renzis, Costantino [1 ,2 ]
Pergolizzi, Stefano [1 ,2 ]
机构
[1] Univ Messina, Dept Biomed Sci & Morphol & Funct Imaging, I-98125 Messina, Italy
[2] Univ Hosp G Martino, Radiotherapy Unit, Messina, Italy
关键词
Radiotherapy; Monte Carlo; dose; fiducial marker x-rays; RADIATION-THERAPY; DOSIMETRIC IMPACT; PROSTATE-CANCER; RADIOTHERAPY; SEED; NANOPARTICLES; LOCALIZATION; FEASIBILITY; VALIDATION; TOOLKIT;
D O I
10.3233/XST-150476
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
OBJECTIVE: Purpose of this work was to study the dose perturbation within the target volume of a external MV radiation therapy when using metal fiducials. METHODS: We developed a Monte Carlo simulation in Geant4 of a cylindrical fiducial made either of gold or of steel and simulated the photon irradiation beam originating from a medical Linac operating at 6, 10 or 15 MV. For each energy, two different irradiation schemes were simulated: a single 5 x 5-cm square field in the -x direction, and five 5 x 5-cm fields at 0 degrees, 80 degrees, 165 degrees, 195 degrees and 280 degrees. RESULTS: In a single beam irradiation scheme, we observed a dose reduction behind fiducials varying from -20% for gold at 6 MV to -5% for steel at 15 MV, and a dose increment in front of the fiducial ranging from +33% for gold at 15 MV to +10% for steel at 6 MV. When five beams were employed, a dose increment ranging from +28% to +46% has been found around gold. Around a steel fiducial, an average increment of +17% was found, irrespective of the photon energy. CONCLUSIONS: When using a single beam, the decrement of dose behind both steel and gold markers increases with the photon energy. This effect vanishes when a multifield treatment is delivered; in this instance there is a dose increment around fiducials, according to both fiducial material and photon energy, with lower values for steel and 6 MV. This energy represents the best choice when fiducial markers are present inside the irradiated volume.
引用
收藏
页码:135 / 140
页数:6
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