Serum zinc levels in hospitalized children with pneumonia: a hospital-based case-control study

被引:4
作者
Hamed, Amira M. M. [1 ]
Kassem, Yasser T. [1 ]
Fayed, Hamada K. [2 ]
Solaiman, Ahmed M. [3 ]
机构
[1] Al Azhar Univ Hosp, Dept Pediat & Neonatol Dept, Assiut, Egypt
[2] Al Azhar Univ Hosp, Dept Chest Dis, Al Forsan Bldg,Al Azhar St, Assiut, Egypt
[3] Al Azhar Univ Hosp, Dept Clin Pathol, Assiut, Egypt
关键词
children; breastfeeding; pneumonia; zinc; DOUBLE-BLIND; YOUNG-CHILDREN; SUPPLEMENTATION; INFECTIONS; DEFICIENCY; EFFICACY; TRIAL;
D O I
10.4103/ejb.ejb_30_19
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Background Zinc is an important micronutrient in humans. Globally, pneumonia represents 18% of mortality in children under 5 years of age and the main infectious purpose of early life mortality. There is a higher pneumonia risk in a population with zinc deficiency. The aim of our study is to compare the level of serum zinc in children with pneumonia with age, sex, and nutritional matched healthy controls. Patients and methods Serum zinc level in 90 children admitted with pneumonia was compared with the matched controls. Results The mean level of serum zinc in children with pneumonia (67.5 +/- 21.8) is significantly lower than that of controls (91.8 +/- 19.94) with (P<0.001). Conclusion Children with pneumonia has a significantly lower serum zinc levels than matched healthy controls.
引用
收藏
页码:730 / 737
页数:8
相关论文
共 31 条
  • [21] Low serum zinc level: The relationship with severe pneumonia and survival in critically ill children
    Saleh, Nagwan Yossery
    El Fotoh, Wafaa Moustafa M. Abo
    [J]. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE, 2018, 72 (06)
  • [22] Role of zinc in severe pneumonia: a randomized double bind placebo controlled study
    Shah, Gauri S.
    Dutta, Ashok K.
    Shah, Dheeraj
    Mishra, Om P.
    [J]. ITALIAN JOURNAL OF PEDIATRICS, 2012, 38
  • [23] Shakur Md Salim, 2004, Indian Pediatr, V41, P478
  • [24] Serum and hair zinc in severely malnourished Bangladeshi children associated with or without acute lower respiratory infection
    Shakur, Md Salim
    Malek, M. A.
    Bano, Nasreen
    Rahman, Mahbubur
    Ahmed, Mesbahuddin
    [J]. INDIAN JOURNAL OF PEDIATRICS, 2009, 76 (06) : 609 - 614
  • [25] Zinc and immune function: the biological basis of altered resistance to infection
    Shankar, AH
    Prasad, AS
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 1998, 68 (02) : 447S - 463S
  • [26] Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial
    Srinivasan, Maheswari G.
    Ndeezi, Grace
    Mboijana, Cordelia Katureebe
    Kiguli, Sarah
    Bimenya, Gabriel S.
    Nankabirwa, Victoria
    Tumwine, James K.
    [J]. BMC MEDICINE, 2012, 10
  • [27] Vakili R, 2009, IRAN J PEDIATR, V19, P376
  • [28] A randomized controlled trial of the effect of zinc as adjuvant therapy in children 2-35 mo of age with severe or nonsevere pneumonia in Bhaktapur, Nepal
    Valentiner-Branth, Palle
    Shrestha, Prakash S.
    Chandyo, Ram K.
    Mathisen, Maria
    Basnet, Sudha
    Bhandari, Nita
    Adhikari, Ramesh K.
    Sommerfelt, Halvor
    Strand, Tor A.
    [J]. AMERICAN JOURNAL OF CLINICAL NUTRITION, 2010, 91 (06) : 1667 - 1674
  • [29] Zinc and the risk for infectious disease
    Walker, CF
    Black, RE
    [J]. ANNUAL REVIEW OF NUTRITION, 2004, 24 : 255 - 275
  • [30] Host defense in respiratory infections
    Welsh, DA
    Mason, CM
    [J]. MEDICAL CLINICS OF NORTH AMERICA, 2001, 85 (06) : 1329 - +