Direct resolution of novel tetrahedral metal clusters on a cellulose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase by high-performance liquid chromatography

被引：1

作者：

Zhu, XY ^{[1
]}

Cai, YC ^{[1
]}

Zhang, WQ ^{[1
]}

Chen, LR ^{[1
]}

Li, YM ^{[1
]}

机构：

[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF SEPARATION SCIENCE | 2003年 / 26卷 / 12-13期

关键词：

chiral stationary phase; cellulose tris-(3,5-dimethylphenylcarbamate); mobile-phase composition; chiral tetrahedral clusters; enantioseparation; HPLC;

D O I：

10.1002/jssc.200301522

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Direct optical resolution of five novel tetrahedral heterometal cluster enantiomers has been achieved for the first time on a cellulose tris-(3,5-dimethylphenylcarbamate) chiral stationary phase, using hexane as the mobile phase with various alcohols as modifiers. UV detection was carried out at 254 nm. The influence of the mobile phase composition on enantioselectivity is discussed and optimum resolution has been achieved. The effect of structural variation of the solutes on their enantioseparation has also been investigated.

引用

页码：1207 / 1210

页数：4

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